Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714187 | 1.00 | KDM4E (0.52) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL16714170 | 0.98 | KDM4E (0.54) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL16714171 | 0.98 | KDM4E (0.54) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL29449353 | 0.89 | KDM4E (0.63) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL85678 | 0.89 | KDM4E (0.63) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL31281511 | 0.89 | KDM4E (0.63) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL385469 | 0.89 | KDM4E (0.63) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL29389834 | 0.89 | KDM4E (0.63) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL13013216 | 0.85 | KDM4E (0.59) | KDM4EPOLBHTTPKMALDH1A1 | |
| SCHEMBL133176 | 0.85 | KDM4E (0.65) | KDM4EPOLBHTTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150137083-A1 | CONJUGATED AROMATIC DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | NATIONAL TSING HUA UNIVERSITY (TW) | 2015-05-21 | — | — | US | disclosed |