Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 16/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 13/20 | 1.00 |
| ▸ | SLC6A5 | Q9Y345 | 12/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556683 | 1.00 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5557243 | 1.00 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5556686 | 1.00 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5562223 | 0.94 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5562471 | 0.93 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5556036 | 0.93 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5556040 | 0.93 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5556905 | 0.93 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5556909 | 0.93 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 | |
| SCHEMBL5562468 | 0.93 | SLC6A9 (1.00) | SLC6A9OPRM1OPRL1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141462-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING DRUG ADDICTION AND PREVENTING A DRUG RELAPSE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-21 | — | — | US | disclosed |