SCHEMBL16714742

SCHEMBL16714742

CO[Si](C)(C)CCCC1CCCNC1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.43
HRH4 Q9H3N8 2/20 0.39
NAAA Q02083 1/20 0.38
EED O75530 1/20 0.37
ACP1 P24666 11/20 0.36
KMT2A Q03164 1/20 0.35
NPY1R P25929 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16714730 0.87 HRH3 (0.43) HRH3HRH4NAAAEEDACP1
SCHEMBL16714829 0.85 HRH3 (0.44) HRH3HRH4NAAAEEDACP1
SCHEMBL16714781 0.84 HRH3 (0.42) HRH3HRH4NAAAACP1KMT2A
SCHEMBL29193075 0.81 HRH3 (0.42) HRH3HRH4NAAAEEDACP1
SCHEMBL16714853 0.78 HRH3 (0.42) HRH3HRH4NAAAACP1KMT2A
SCHEMBL3918708 0.77 SLC6A1 (0.34) HRH3HRH4
SCHEMBL7704486 0.76 HRH3 (0.53) HRH3HRH4NAAAEEDACP1
SCHEMBL16714788 0.76 HRH3 (0.43) HRH3HRH4NAAAEEDACP1
SCHEMBL5234321 0.76 HRH3 (0.44) HRH3HRH4NAAAEEDACP1
SCHEMBL3911210 0.75 SLC6A1 (0.35) HRH3HRH4EEDACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862812-B2 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2876111-B1 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO (JP) 2017-09-20 EP disclosed
EP-2876111-A1 Composition containing nitrogen-containing organoxysilane compound and method for making the same Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-27 EP disclosed
US-20150135996-A1 COMPOSITION CONTAINING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND AND METHOD FOR MAKING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-21 US disclosed