⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013021 | 0.92 | — | — | |
| SCHEMBL8007311 | 0.91 | — | — | |
| SCHEMBL8007854 | 0.91 | AGTR1 (0.37) | — | |
| SCHEMBL8007768 | 0.91 | — | — | |
| SCHEMBL7998174 | 0.90 | — | — | |
| SCHEMBL8434189 | 0.89 | — | — | |
| Potassium SCHEMBL8911660 | 0.89 | — | — | |
| Embusartan SCHEMBL5537214 | 0.89 | — | — | |
| SCHEMBL8894371 | 0.89 | — | — | |
| SCHEMBL8009771 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1719 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250082608-A1 | TREATMENT AND PREVENTION OF GLOMERULAR DISEASE | SINGAPORE HEALTH SERVICES PTE LTD. (SG) | 2025-03-13 | — | — | US | claimed |
| EP-4448096-A1 | TREATMENT AND PREVENTION OF GLOMERULAR DISEASE | Singapore Health Services Pte. Ltd. (SG) | 2024-10-23 | — | — | EP | claimed |
| US-12064429-B2 | Substituted 5-fluoro-1H-pyrazolopyridines and their use | ADVERIO PHARMA GMBH (DE) | 2024-08-20 | — | — | US | claimed |
| US-12016835-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2024-06-25 | — | — | US | claimed |
| US-20240173302-A1 | TREATMENT OF INFLAMMATORY DISEASES | DIMERIX BIOSCIENCE PTY LTD. (AU) | 2024-05-30 | — | — | US | claimed |
| EP-4313024-A1 | TREATMENT OF INFLAMMATORY DISEASES | Dimerix Bioscience Pty Ltd (AU) | 2024-02-07 | — | — | EP | claimed |
| US-11851443-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-12-26 | — | — | US | claimed |
| US-20230285340-A1 | NEPRILYSIN INHIBITORS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2023-09-14 | — | — | US | claimed |
| US-11718591-B2 | Crystalline (2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2- methylpentanoic acid and uses thereof | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-08-08 | — | — | US | claimed |
| WO-2023111196-A1 | TREATMENT AND PREVENTION OF GLOMERULAR DISEASE | SINGAPORE HEALTH SERVICES PTE. LTD. (SG) | 2023-06-22 | — | — | WO | claimed |
| EP-1627638-A1 | FORTIFIER | TORAY INDUSTRIES, INC. (JP) | 2006-02-22 | — | — | EP | claimed |
| WO-2006000564-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NEP-INHIBITORS, INHIBITORS OF THE ENDOGENOUS ENDOTHELIN PRODUCING SYSTEM AND AT1-RECEPTOR ANTAGONISTS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2006-01-05 | — | — | WO | claimed |
| US-20050288272-A1 | Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and AT1 receptor antagonists | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-12-29 | — | — | US | claimed |
| EP-1545540-A2 | COMBINATION THERAPY USING A DUAL PPAR ALPHA/GAMMA AGONIST AND AN ANGIOTENSIN II TYPE I RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2005023182-A2 | NITROSATED AND NITROSYLATED CARDIOVASCULAR COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2005-03-17 | — | — | WO | claimed |
| WO-2004080488-A2 | COMBINED PREPARATIONS OF ACETYL SALICYLIC ACID WITH AN HMG-COA REDUCTASE INHIBITOR | BAYER HEALTHCARE AG (DE) | 2004-09-23 | — | — | WO | claimed |
| WO-2004017896-A2 | COMBINATION THERAPY USING A DUAL PPAR ALPHA/GAMMA AGONIST AND AN ANGIOTENSIN II TYPE I RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 2004-03-04 | — | — | WO | claimed |
| EP-1258258-A1 | Implantable device comprising a stent and angiotensin II receptor antagonists | TERUMO KABUSHIKI KAISHA (JP) | 2002-11-20 | — | — | EP | claimed |
| US-20020168393-A1 | Implantable medical material and implantable medical device | TERUMO KABUSHIKI KAISHA (JP) | 2002-11-14 | — | — | US | claimed |
| WO-2000037075-A1 | COMBINATION OF AN AT1 ANGIOTENSIN II RECEPTOR ANTAGONIST AND AN IMMUNOSUPPRESSANT | SANOFI-SYNTHELABO (FR) | 2000-06-29 | — | — | WO | claimed |