SCHEMBL16715481

SCHEMBL16715481

O=S(=O)(Nc1ccc(F)cc1)c1ccc2c(c1)CCN(CCc1ccc(-c3cccnc3)cc1)C2

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MOGAT2 Q3SYC2 15/20 0.68
ABCB1 P08183 4/20 0.46
ABCG2 Q9UNQ0 1/20 0.45
OGG1 O15527 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15435191 0.90 MOGAT2 (0.75) MOGAT2ABCB1
SCHEMBL15435261 0.83 MOGAT2 (0.81) MOGAT2
SCHEMBL15435356 0.83 MOGAT2 (0.78) MOGAT2
SCHEMBL15399493 0.82 MOGAT2 (0.84) MOGAT2
SCHEMBL16715563 0.81 MOGAT2 (0.72) MOGAT2
SCHEMBL15399787 0.81 MOGAT2 (1.00) MOGAT2
SCHEMBL15435246 0.81 MOGAT2 (0.77) MOGAT2ABCB1
SCHEMBL16715479 0.81 MOGAT2 (0.77) MOGAT2
SCHEMBL16715564 0.80 MOGAT2 (0.79) MOGAT2
SCHEMBL15435280 0.80 MOGAT2 (0.75) MOGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035059-B2 Nitrogen-containing condensed heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-05-19 US disclosed
US-9035059-B2 Nitrogen-containing condensed heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-05-19 US disclosed