Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 16/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715481 | 0.90 | MOGAT2 (0.68) | MOGAT2ABCB1 | |
| SCHEMBL15435261 | 0.89 | MOGAT2 (0.81) | MOGAT2 | |
| SCHEMBL15435356 | 0.89 | MOGAT2 (0.78) | MOGAT2DRD2DRD3HTR6 | |
| SCHEMBL15399493 | 0.87 | MOGAT2 (0.84) | MOGAT2 | |
| SCHEMBL15399787 | 0.86 | MOGAT2 (1.00) | MOGAT2 | |
| SCHEMBL16715479 | 0.86 | MOGAT2 (0.77) | MOGAT2 | |
| SCHEMBL15435246 | 0.86 | MOGAT2 (0.77) | MOGAT2ABCB1 | |
| SCHEMBL15435172 | 0.85 | MOGAT2 (0.56) | MOGAT2ABCB1MLNRDRD2DRD3 | |
| SCHEMBL16715478 | 0.84 | MOGAT2 (0.75) | MOGAT2 | |
| SCHEMBL15435427 | 0.84 | MOGAT2 (0.63) | MOGAT2ABCB1MGAT2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2687507-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |