SCHEMBL16716006

SCHEMBL16716006

CCC#Cc1cn([C@H]2C[C@@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.57
POLA1 P09884 1/20 0.55
POLD1 P28340 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8600185 0.93 POLB (0.56) POLBPOLA1POLD1
SCHEMBL8600188 0.93 POLB (0.56) POLBPOLA1POLD1
SCHEMBL21585110 0.92 POLB (0.54) POLBPOLA1POLD1
SCHEMBL17525803 0.91 POLB (0.55) POLBPOLA1POLD1
SCHEMBL304478 0.91 POLB (0.55) POLBPOLA1POLD1
SCHEMBL15740088 0.91 POLB (0.55) POLB
SCHEMBL17229171 0.91 POLB (0.55) POLBPOLA1POLD1
SCHEMBL13314185 0.91 POLB (0.55) POLBPOLA1POLD1
SCHEMBL14438987 0.91 POLB (0.55) POLBPOLA1POLD1
SCHEMBL304477 0.91 POLB (0.55) POLBPOLA1POLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035035-B2 Macromolecular nucleotide compounds and methods for using the same GENOVOXX GMBH (DE) 2015-05-19 US disclosed