Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | POLD1 | P28340 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600188 | 1.00 | POLB (0.56) | POLBPOLA1POLD1 | |
| SCHEMBL21585110 | 0.95 | POLB (0.54) | POLBPOLA1POLD1 | |
| SCHEMBL16716006 | 0.93 | POLB (0.57) | POLBPOLA1POLD1 | |
| SCHEMBL17123701 | 0.92 | POLB (0.53) | POLB | |
| SCHEMBL20074276 | 0.91 | POLB (0.53) | POLB | |
| SCHEMBL16638689 | 0.91 | POLB (0.53) | POLB | |
| SCHEMBL10046514 | 0.91 | POLB (0.53) | POLB | |
| SCHEMBL17123697 | 0.91 | POLB (0.53) | POLBPOLA1POLD1 | |
| SCHEMBL17123671 | 0.90 | POLB (0.53) | POLBPOLA1POLD1 | |
| SCHEMBL17525803 | 0.90 | POLB (0.55) | POLBPOLA1POLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756291-A | IDENTIFYING OLIGOMER SEQUENCES; QUALITATIVE ANALYSIS; ANALYSIS OF THROMBIN BY COMPLEXING | GILEAD SCIENCES, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0572529-A1 | APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING | GILEAD SCIENCES, INC. (US) | 1993-12-08 | — | — | EP | disclosed |
| WO-1992014842-A1 | APTAMERS SPECIFIC FOR THROMBIN AND METHODS OF USE | GILEAD SCIENCES, INC. (US) | 1992-09-03 | — | — | WO | disclosed |
| WO-1992014843-A1 | APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING | GILEAD SCIENCES, INC. (US) | 1992-09-03 | — | — | WO | disclosed |