Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 14/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16716540 | 0.92 | TAS2R8 (0.64) | TAS2R8CREBBP | |
| SCHEMBL16716547 | 0.87 | TAS2R8 (0.66) | TAS2R8 | |
| SCHEMBL1279498 | 0.79 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL16716557 | 0.78 | TAS2R8 (0.48) | TAS2R8ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL1279293 | 0.74 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1278900 | 0.72 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279646 | 0.71 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1655607 | 0.70 | TAS2R8 (0.61) | TAS2R8ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL1279790 | 0.69 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279587 | 0.69 | TAS2R8 (1.00) | TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487169-B1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | SENOMYX INC (US) | 2015-05-20 | — | — | EP | disclosed |