SCHEMBL16716556

SCHEMBL16716556

C=C1N(c2cnn(Cc3c(C)noc3C)c2)C(=O)N(CCOc2ccccc2)N1C

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TAS2R8 Q9NYW2 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13940245 0.81 TAS2R8 (0.69) TAS2R8
SCHEMBL1279677 0.81 TAS2R8 (1.00) TAS2R8
SCHEMBL1279617 0.80 TAS2R8 (1.00) TAS2R8
SCHEMBL10247652 0.78 TAS2R8 (0.59) TAS2R8
SCHEMBL1279140 0.78 TAS2R8 (1.00) TAS2R8
SCHEMBL17480041 0.77 TAS2R8 (0.72) TAS2R8
SCHEMBL3677599 0.75 TAS2R8 (0.64) TAS2R8
SCHEMBL1279309 0.74 TAS2R8 (1.00) TAS2R8
SCHEMBL12290402 0.74 TAS2R8 (0.84) TAS2R8
SCHEMBL13940178 0.74 TAS2R8 (0.63) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2487169-B1 Compounds that inhibit (block) bitter taste in compositions and use thereof SENOMYX INC (US) 2015-05-20 — — EP disclosed
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