SCHEMBL16716617

SCHEMBL16716617

CC=C1NC(CC2CCCC2)C(=O)N1c1cnn(Cc2c(C)noc2C)c1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TAS2R8 Q9NYW2 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1279076 0.92 TAS2R8 (1.00) TAS2R8
SCHEMBL1279237 0.91 TAS2R8 (1.00) TAS2R8
SCHEMBL12289326 0.88 TAS2R8 (0.86) TAS2R8
SCHEMBL13939298 0.86 TAS2R8 (0.82) TAS2R8
SCHEMBL12289821 0.81 TAS2R8 (0.85) TAS2R8
SCHEMBL16716577 0.80 TAS2R8 (0.86) TAS2R8
SCHEMBL1279297 0.77 TAS2R8 (1.00) TAS2R8
SCHEMBL18351073 0.77 TAS2R8 (0.80) TAS2R8
SCHEMBL1278689 0.76 TAS2R8 (1.00) TAS2R8
SCHEMBL1279213 0.74 TAS2R8 (1.00) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2487169-B1 Compounds that inhibit (block) bitter taste in compositions and use thereof SENOMYX INC (US) 2015-05-20 EP disclosed