⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424808 | 0.79 | — | — | |
| SCHEMBL2596768 | 0.79 | — | — | |
| SCHEMBL7757077 | 0.74 | — | — | |
| SCHEMBL265179 | 0.73 | — | — | |
| SCHEMBL248830 | 0.69 | — | — | |
| SCHEMBL3212874 | 0.69 | — | — | |
| SCHEMBL60586 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL25264251 | 0.65 | — | — | |
| Bromide SCHEMBL8879721 | 0.65 | — | — | |
| SCHEMBL16179432 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116881-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| WO-2025011523-A1 | REFLECTING DEVICE, MANUFACTURING METHOD FOR REFLECTING DEVICE, AND VEHICLE | 比亚迪股份有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-118271311-A | Anodic electrochromic material, electrochromic composition and electrochromic device | 比亚迪股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| US-20240059676-A1 | THYROID HORMONE RECEPTOR b SELECTIVE AGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2024-02-22 | — | — | US | disclosed |
| CN-114634486-B | Thyroxine receptor beta selective agonist compounds, pharmaceutical compositions and uses thereof | 中国科学院上海药物研究所 | 2024-01-30 | — | — | CN | disclosed |
| EP-4265609-A1 | THYROID HORMONE RECEPTOR BETA SELECTIVE AGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-10-25 | — | — | EP | disclosed |
| CN-116925045-A | Thyroxine receptor beta selective agonist compounds, pharmaceutical compositions and uses thereof | 中国科学院上海药物研究所 | 2023-10-24 | — | — | CN | disclosed |
| WO-2022127699-A1 | THYROID HORMONE RECEPTOR β SELECTIVE AGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2022-06-23 | — | — | WO | disclosed |
| CN-114634486-A | Thyroxine receptor beta selective agonist compounds, pharmaceutical compositions and uses thereof | 中国科学院上海药物研究所 | 2022-06-17 | — | — | CN | disclosed |
| WO-2019183367-A1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| EP-3071203-A2 | TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | Forma Therapeutics, Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015074064-A2 | TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BAIR KENNETH W (US) | 2015-05-21 | — | — | WO | disclosed |