Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877718 | 0.73 | BRD4 (0.53) | BRD4MC4RKDM4EKMT2ACASP1 | |
| SCHEMBL1521829 | 0.71 | BRD4 (0.44) | BRD4LPOHDAC4KDM4EKMT2A | |
| SCHEMBL16719473 | 0.70 | CYP19A1 (0.38) | KDM4EKMT2AHSD17B10L3MBTL1NPC1 | |
| SCHEMBL28357972 | 0.69 | BRD4 (0.38) | BRD4LPOHDAC4KDM4EKMT2A | |
| SCHEMBL16720657 | 0.68 | IDO1 (0.57) | BRD4HTR2AHTR2C | |
| SCHEMBL16720187 | 0.68 | BRD4 (0.41) | BRD4LPOHDAC4MC4RKDM4E | |
| SCHEMBL308400 | 0.67 | LPO (0.55) | BRD4LPOHDAC4KDM4EKMT2A | |
| SCHEMBL2874163 | 0.67 | HDAC4 (0.40) | BRD4LPOHDAC4KDM4EKMT2A | |
| SCHEMBL16720807 | 0.66 | KDM4E (0.46) | KDM4EHSD17B10L3MBTL1NPC1PKM | |
| Hydrochloric Acid SCHEMBL1806963 | 0.65 | LPO (0.52) | BRD4LPOHDAC4KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |