Glutamic Acid

Glutamic Acid

SCHEMBL1672085

N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CO)C(=O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.82
GRM6 O15303 2/20 0.82
GRM7 Q14831 2/20 0.82
GRM4 Q14833 2/20 0.82
GSR P00390 2/20 0.82
GRIN2D O15399 1/20 0.82
GRIN3B O60391 1/20 0.82
CYP1A2 P05177 1/20 0.82
GRIK1 P39086 1/20 0.82
GRM5 P41594 1/20 0.82
GRIA1 P42261 1/20 0.82
GRIA2 P42262 1/20 0.82
GRIA3 P42263 1/20 0.82
SLC1A3 P43003 1/20 0.82
SLC1A2 P43004 1/20 0.82
SLC1A1 P43005 1/20 0.82
GRIA4 P48058 1/20 0.82
GRIN1 Q05586 1/20 0.82
GRIN2A Q12879 1/20 0.82
GRIK2 Q13002 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL23454457 1.00 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1672084 1.00 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL9617055 0.94 GRM8 (0.72) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL4195596 0.94 GRM8 (0.72) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL21569403 0.92 CYP1A2 (0.69) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL20766626 0.92 GRM8 (0.69) GRM8GRM6GRM7GRM4GSR
Glutamine SCHEMBL28408963 0.92 PMP22 (0.73) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330484 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330824 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL931953 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444736-A Polyamino acid-like macromolecule and preparation method and application thereof 临沂大学 2023-07-18 CN claimed
WO-2020009165-A1 MODIFIED ANTIBODY AND METHOD FOR PRODUCING SAME 味の素株式会社 2020-01-09 WO claimed
US-20240200041-A1 Modified Pyrococcus Polymerases and Uses Thereof FIRST-CITIZENS BANK & TRUST COMPANY 2024-06-20 US disclosed
US-20240182875-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2024-06-06 US disclosed
US-20240141171-A1 USE OF FERMENTED MOLASSES AS AN EMULSIFIER LESAFFRE ET COMPAGNIE (FR) 2024-05-02 US disclosed
EP-4347715-A1 USE OF FERMENTED MOLASSES AS AN EMULSIFIER Lesaffre et Compagnie (FR) 2024-04-10 EP disclosed
US-11891633-B2 Modified pyrococcus polymerases and uses thereof Singular Genomics Systems, Inc. (US) 2024-02-06 US disclosed
US-11884943-B2 Engineered Pyrococcus enzymes and uses thereof Singular Genomics Systems, Inc. (US) 2024-01-30 US disclosed
EP-4025185-B1 PARENTERAL NUTRITION FORMULATION WITH OPTIMIZED AMINO ACID AND GLUCOSE CONTENT BAXTER INT (US) 2024-01-17 EP disclosed
US-11851687-B2 Modified Pyrococcus polymerases and uses thereof Singular Genomics Systems, Inc. (US) 2023-12-26 US disclosed
WO-2023131764-A1 FERMENTED MOLASSES COMPOSITION, AND USES THEREOF LESAFFRE ET COMPAGNIE (FR) 2023-07-13 WO disclosed
US-20100240085-A1 CONJUGATE MOLECULES DAKO DENMARK APS (DK) 2010-09-23 US disclosed
US-20100240047-A1 METHODS AND COMPOUNDS FOR DETECTION OF MOLECULAR TARGETS DAKO DENMARK APS (DK) 2010-09-23 US disclosed
WO-2010094284-A1 METHODS AND COMPOUNDS FOR DETECTION OF MOLECULAR TARGETS DAKO DENMARK A/S (DK) 2010-08-26 WO disclosed
WO-2010094283-A1 CONJUGATE MOLECULES DAKO DENMARK A/S (DK) 2010-08-26 WO disclosed
CN-1826129-A Methods and compositions relating to isoleucine boroproline compounds POINT THERAPEUTICS INC (US) 2006-08-30 CN disclosed
WO-2004080920-A1 HYDROPONIC PLANT NUTRIENT KIT AND METHOD OF USE ADVANCED NUTRIENTS LTD. (CA) 2004-09-23 WO disclosed
CN-1370235-A Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production BASF AG (DE) 2002-09-18 CN disclosed
CN-1042930-A The preparation of rare earth addition and application WU JIAN (CN) 1990-06-13 CN disclosed
US-4623623-A PROTOPLAST FUSION OF CORYNEBACTERIUM AND BREVIBACTERIUM, ANTIBIOTIC RESISTANCE KYOWA HAKKO KOGYO CO., LTD. (JP) 1986-11-18 US disclosed