D-Glutamate

D-Glutamate

SCHEMBL931953

NC(CCC(=O)O)C(=O)O.NC(CCC(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM8 O00222 2/20 1.00
▸ GRM6 O15303 2/20 1.00
▸ GRM7 Q14831 2/20 1.00
▸ GRM4 Q14833 2/20 1.00
▸ GRIN2D O15399 1/20 1.00
▸ GRIN3B O60391 1/20 1.00
▸ GSR P00390 1/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ GRIK1 P39086 1/20 1.00
▸ GRM5 P41594 1/20 1.00
▸ GRIA1 P42261 1/20 1.00
▸ GRIA2 P42262 1/20 1.00
▸ GRIA3 P42263 1/20 1.00
▸ SLC1A3 P43003 1/20 1.00
▸ SLC1A2 P43004 1/20 1.00
▸ SLC1A1 P43005 1/20 1.00
▸ GRIA4 P48058 1/20 1.00
▸ GRIN1 Q05586 1/20 1.00
▸ GRIN2A Q12879 1/20 1.00
▸ GRIK2 Q13002 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL1554237 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332007 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332297 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL43222 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL2202 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332144 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL410241 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL5704264 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330566 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330917 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023240022-A2 CONJUGATE FOR TARGETING CENTRAL NERVOUS SYSTEM SUNTEC MEDICAL, INC. (US) 2023-12-14 — — WO claimed
CN-112961848-B Novel aminopeptidase and soluble expression method thereof 中国海洋大学 2022-09-09 — — CN claimed
CN-103405753-B Stable insulin secretion accelerating peptide liquid drugs injection pharmaceutical composition Shanghai Renhui biological pharmaceutical Co., Ltd. (CN) 2016-05-11 — — CN claimed
US-8501679-B2 Cyclic, cystein-free protein APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH (AT) 2013-08-06 — — US claimed
EP-2217619-B1 CYCLIC, CYSTEIN-FREE PROTEIN APEPTICO FORSCHUNG & ENTWICKLUNG GMBH (AT) 2012-11-07 — — EP claimed
CN-101781325-B Gallium salicylaldehyde amino acid Schiff base quaternary complex and preparation method and application thereof UNIV BEIJING NORMAL 2012-05-16 — — CN claimed
US-20110105414-A1 CYCLIC, CYSTEIN-FREE PROTEIN APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH (AT) 2011-05-05 — — US claimed
US-7585333-B2 Fluorescent whitening agent, for whitening synthetic or natural organic materials, especially paper and for the fluorescent whitening and improvement of sun protection factors of textile materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-08 — — US claimed
US-20080307585-A1 Fluorescent whitening agent, for whitening synthetic or natural organic materials, especially paper and for the fluorescent whitening and improvement of sun protection factors of textile materials CIBA SPECIALTY CHEMICALS CORP. 2008-12-18 — — US claimed
EP-3995588-B1 LIBRARY CREATION METHOD AND APPLICATION GENETRON HEALTH BEIJING CO LTD (CN) 2025-12-17 — — EP disclosed
WO-2025035113-A2 CONFIRMATION OF PROTEIN IDENTIFICATION AND PURITY THROUGH COMPARABILITY PROTEIN DYNAMIC SOLUTIONS, INC. (US) 2025-02-13 — — WO disclosed
WO-2024243201-A2 A METHOD OF PROVIDING EARLY INTERVENTION TO A NEWBORN OR INFANT WITH AUTISM SPECTRUM DISORDER THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-11-28 — — WO disclosed
US-11985994-B2 Sweetener and flavor compositions, methods of making and methods of use thereof EPC Natural Products Co., Ltd (CN) 2024-05-21 — — US disclosed
EP-4352037-A1 CARBOXYLIC ACID LOADED SALT CARRIER AND THE METHOD FOR PRODUCING THEREOF BRENDLER, Lucas (DE) 2024-04-17 — — EP disclosed
CN-1282372-A mammalian cytokine-like polypeptide-10 ZYMOGENETICS INC (US) 2001-01-31 — — CN disclosed
CN-1258315-A Mammalian cytokine-like factor 7 ZYMOGENETICS INC (US) 2000-06-28 — — CN disclosed
EP-0410881-B1 Semisynthetic ganglioside analogues FIDIA SPA (IT) 1997-09-17 — — EP disclosed
WO-1994017198-A1 ENZYMATIC FLUOROMETRIC ASSAY FOR ADENYLATE CYCLASE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1994-08-04 — — WO disclosed
US-4766071-A USING ALKANOLS AND ALKANALS AND ENZYME OBTAINED BY LYSIS OF CELL SUSPENSION HENKEL KOMMANDITGESELLSHAFT AUF AKTIEN (DE) 1988-08-23 — — US disclosed
EP-0110049-A2 Mixed seasoning INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-06-13 — — EP disclosed
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