Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 6/20 | 0.49 |
| ▸ | IKBKB | O14920 | 3/20 | 0.49 |
| ▸ | CHUK | O15111 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.49 |
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | LTK | P29376 | 1/20 | 0.49 |
| ▸ | GRK5 | P34947 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240671 | 0.79 | AURKB (0.71) | NUDT1IKBKBCHUKAURKBIGF1R | |
| SCHEMBL857435 | 0.78 | IKBKB (0.63) | NUDT1IKBKBCHUKAURKBIGF1R | |
| SCHEMBL16719631 | 0.78 | CDC7 (0.51) | DAPK3MAP4K4RETPRKACACDK8 | |
| Water SCHEMBL29822295 | 0.73 | PRKCI (0.57) | NUDT1IKBKBCHUKAURKBIGF1R | |
| SCHEMBL16719560 | 0.73 | PIK3CD (0.44) | — | |
| SCHEMBL16720891 | 0.72 | NUDT1 (0.51) | NUDT1IKBKBCHUKAURKBIGF1R | |
| SCHEMBL1269968 | 0.71 | PRKCI (0.59) | NUDT1IKBKBCHUKAURKBIGF1R | |
| SCHEMBL31065020 | 0.70 | IKBKB (0.70) | NUDT1IKBKBCHUKAURKBIGF1R | |
| SCHEMBL4771643 | 0.70 | IKBKB (0.70) | NUDT1IKBKBCHUKAURKBIGF1R | |
| SCHEMBL16720661 | 0.69 | BRD4 (0.38) | NUDT1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |