Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 19/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16722011 | 0.93 | S1PR1 (0.49) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL16722331 | 0.88 | S1PR5 (0.59) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16722258 | 0.84 | S1PR5 (0.52) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL16722437 | 0.82 | S1PR5 (0.54) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16722188 | 0.82 | S1PR5 (0.56) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16722681 | 0.80 | S1PR5 (0.56) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16719312 | 0.79 | S1PR1 (0.53) | S1PR1S1PR3 | |
| SCHEMBL10060820 | 0.79 | S1PR1 (0.52) | S1PR5S1PR1 | |
| SCHEMBL16722661 | 0.78 | S1PR5 (0.56) | S1PR5S1PR1S1PR3 | |
| SCHEMBL16445863 | 0.78 | S1PR5 (0.55) | S1PR5S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073547-A1 | DISUBSTITUTED PHENOXY AZETIDINE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | claimed |
| WO-2015073547-A1 | DISUBSTITUTED PHENOXY AZETIDINE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | disclosed |
| WO-2015073547-A1 | DISUBSTITUTED PHENOXY AZETIDINE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | disclosed |