Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723237 | 0.85 | MAPT (0.40) | MAPTGAATSHR | |
| SCHEMBL16723031 | 0.85 | HCRTR2 (0.34) | — | |
| SCHEMBL16722934 | 0.82 | GAA (0.40) | MAPTGAATSHR | |
| SCHEMBL16723361 | 0.82 | MAPT (0.37) | MAPTGAATSHR | |
| SCHEMBL16723306 | 0.82 | MAPT (0.37) | MAPTGAATSHR | |
| SCHEMBL16722986 | 0.79 | BRD4 (0.38) | MAPTGAATSHR | |
| SCHEMBL16723345 | 0.78 | GAA (0.36) | MAPTGAATSHR | |
| SCHEMBL16723321 | 0.77 | GAA (0.33) | GAATSHR | |
| SCHEMBL16722956 | 0.77 | HCRTR2 (0.30) | — | |
| SCHEMBL16723286 | 0.76 | MAPT (0.38) | MAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015074081-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BAIR KENNETH W (US) | 2015-05-21 | — | — | WO | disclosed |