Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723287 | 0.78 | FEN1 (0.39) | — | |
| SCHEMBL16723271 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL16723200 | 0.70 | KDM4E (0.32) | — | |
| SCHEMBL26949614 | 0.69 | HRH3 (0.35) | HRH3 | |
| SCHEMBL26950058 | 0.69 | HRH3 (0.35) | HRH3 | |
| SCHEMBL26950060 | 0.69 | HRH3 (0.35) | HRH3 | |
| SCHEMBL26949941 | 0.68 | HRH3 (0.35) | HRH3KCNH2 | |
| SCHEMBL26949456 | 0.68 | HRH3 (0.35) | HRH3KCNH2 | |
| SCHEMBL26949351 | 0.68 | HRH3 (0.35) | HRH3KCNH2 | |
| SCHEMBL16723270 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015074081-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BAIR KENNETH W (US) | 2015-05-21 | — | — | WO | disclosed |