Escin Ia

Escin Ia

SCHEMBL167245

CC=C(C)C(=O)OC1C(OC(C)=O)C2(CO)C(O)CC3(C)C(=CCC4C5(C)CCC(OC6OC(C(=O)O)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6OC6OC(CO)C(O)C(O)C6O)C(C)(CO)C5CCC43C)C2CC1(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 1/20 1.00
APLNR P35414 1/20 1.00
CCR6 P51684 1/20 1.00
TOP1 P11387 13/20 0.90
SLCO1B3 Q9NPD5 1/20 0.81
SLCO1B1 Q9Y6L6 1/20 0.81
CRHBP P24387 2/20 0.76
CRHR2 Q13324 2/20 0.76
F3 P13726 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Escin Ia SCHEMBL13007226 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ia SCHEMBL13990760 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ia SCHEMBL13007215 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ia SCHEMBL18947797 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ia SCHEMBL19361964 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ib SCHEMBL23883543 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ia SCHEMBL6246175 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ib SCHEMBL15531983 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ia SCHEMBL284871 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3
Escin Ia SCHEMBL29434526 1.00 CXCR5 (1.00) CXCR5APLNRCCR6TOP1SLCO1B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3210 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081346-A Horse chestnut tiglyl coenzyme A ligase gene AcCCL, acCCL3 protein and application 2026-05-26 CN claimed
CN-122031742-A Starch film slow-release patch for promoting wound healing and preparation method thereof 咸阳职业技术学院 2026-05-15 CN claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP claimed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP claimed
EP-4635501-A2 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW Sapreme Technologies B.V. (NL) 2025-10-22 EP claimed
EP-4631524-A2 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE Sapreme Technologies B.V. (NL) 2025-10-15 EP claimed
EP-4611763-A1 METHOD FOR PRODUCING NASAL FORMULATION COMPRISING AESCIN AND RUTIN Mousavi Mirzaei, Seyed Mohammad (IR) 2025-09-10 EP claimed
EP-4610278-A2 TARGETED SAPONIN-NUCLEIC ACID CONJUGATES FOR TREATMENT OF MUSCLE WASTING DISORDERS Sapreme Technologies B.V. (NL) 2025-09-03 EP claimed
EP-4596052-A2 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF Sapreme Technologies B.V. (NL) 2025-08-06 EP claimed
EP-4452331-B1 TARGETED SAPONIN-NUCLEIC ACID CONJUGATES FOR TREATMENT OF MUSCLE WASTING DISORDERS SAPREME TECH BV (NL) 2025-08-06 EP claimed
EP-0493151-B1 Slimming composition containing ginkgo biloba as alpha-2 blocker OREAL (FR) 1995-08-02 EP claimed
EP-0283713-B1 COMPLEXES OF SAPONINS WITH PHOSPHOLIPIDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM INDENA S.p.A. (IT) 1993-08-11 EP claimed
US-5118671-A Antiinflammatory agent INDENA S.P.A. (IT) 1992-06-02 US claimed
EP-0231039-B1 PROCESS FOR PREPARING IMMUNOLOGICAL COMPLEXES AND PHARMACEUTICAL COMPOSITION CONTAINING THESE COMPLEXES DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 1992-01-08 EP claimed
EP-0109942-B1 IMMUNOGENIC PROTEIN OR PEPTIDE COMPLEX, METHOD OF PRODUCING SAID COMPLEX AND THE USE THEREOF AS AN IMMUNE STIMULANT AND AS A VACCINE Morein, Bror (SE) 1991-03-06 EP claimed
CN-1048925-A Producing with detection agent (the affinity thing of cholesterol) and visual developer serves as that the basis is used for method and this application of compound at the affinity enzyme compound of the visual demonstration cholesterol of patient skin surface NII FIZ KHIM MEDITSINY (SU) 1991-01-30 CN claimed
EP-0338189-A2 Method of producing affin-enzymatic compounds, for the visual detection of cholesterol on the surface of the skin of a patient, based on a detecting agent with an affinity for cholesterol and a visualisation agent 2860601 Canada Inc. (CN) 1989-10-25 EP claimed
EP-0180564-A2 Immunogenic complex, a method for producing the same, and the use thereof as an immune stimulant, vaccines and reagents Morein, Bror (SE) 1986-05-07 EP claimed
EP-0109942-A2 Immunogenic protein or peptide complex, method of producing said complex and the use thereof as an immune stimulant and as a vaccine Morein, Bror (SE) 1984-05-30 EP claimed
US-4101652-A Pharmaceutically active complexes and pharmaceutical compositions containing eascin and sterols INVERNI DELLA BEFFA S.P.A. (IT) 1978-07-18 US claimed