Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.33 |
| ▸ | PDE5A | O76074 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE1A | P54750 | 3/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16724636 | 0.93 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1PDE5APDE4APDE1A | |
| SCHEMBL16724656 | 0.91 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1PDE5APDE4APDE1A | |
| SCHEMBL16724623 | 0.90 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1PDE5APDE4APDE1A | |
| SCHEMBL16724653 | 0.90 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16724626 | 0.90 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL16724625 | 0.89 | APP (0.36) | HSP90AA1HSP90AB1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16724621 | 0.88 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL16724629 | 0.88 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1PDE5APDE4APDE1A | |
| SCHEMBL16724639 | 0.87 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL16724620 | 0.84 | APP (0.45) | KDM4ERAB9ASMN1; SMN2TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187467-B2 | 2-phenyl benzothiazole linked imidazole compounds as potential anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-11-17 | — | — | US | disclosed |
| US-20150141657-A1 | 2-PHENYL BENZOTHIAZOLE LINKED IMIDAZOLE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141657-A1 | 2-PHENYL BENZOTHIAZOLE LINKED IMIDAZOLE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | NFE2L2, TPT1, CCNT1 | HSP90AA1 206/4885HSP90AB1 115/4885PDE5A 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.