⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555313 | 0.74 | MME (0.42) | — | |
| SCHEMBL348796 | 0.74 | — | — | |
| SCHEMBL11680924 | 0.74 | ALDH1A1 (0.53) | — | |
| SCHEMBL7524768 | 0.72 | — | — | |
| SCHEMBL511965 | 0.72 | — | — | |
| SCHEMBL7519799 | 0.72 | — | — | |
| SCHEMBL11232281 | 0.72 | — | — | |
| SCHEMBL7520045 | 0.72 | — | — | |
| SCHEMBL529911 | 0.72 | — | — | |
| SCHEMBL7524717 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367131-B1 | Light-sensitive composition | BASF AG (DE) | 1995-02-22 | — | — | EP | claimed |
| US-5035979-A | Radiation-sensitive mixture | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-30 | — | — | US | claimed |
| CN-118239891-A | Method for preparing N- (5-pyrimidine methyl) -2-pyridine amine compound | 帕潘纳(北京)科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-106083855-B | Purine derivatives useful as Hsp90 inhibitors | 斯隆-凯特林癌症研究院 | 2020-04-10 | — | — | CN | disclosed |
| CN-106083855-A | Purine derivative as Hsp90 inhibitor | 斯隆-凯特林癌症研究院 | 2016-11-09 | — | — | CN | disclosed |
| CN-105924443-A | Purine derivatives useing as Hsp90 inhibitors | 斯隆-凯特林癌症研究院 | 2016-09-07 | — | — | CN | disclosed |
| EP-2486039-A1 | PURINE DERIVATIVES USEFUL AS HSP90 INHIBITORS | Sloan Kettering Institute For Cancer Research (US) | 2012-08-15 | — | — | EP | disclosed |
| CN-102639534-A | Purine derivatives useful as hsp90 inhibitors | SLOAN KETTERING INST CANCER | 2012-08-15 | — | — | CN | disclosed |
| WO-2011044394-A1 | PURINE DERIVATIVES USEFUL AS HSP90 INHIBITORS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-04-14 | — | — | WO | disclosed |
| US-5440031-A | Form stable complexes with radioactive metal ions which can be eliminated from organism | Orszagos "Frederic Joliot-Curie" Sugar-biologiai es Sugaregeszsegugyi Kutato Intezet (HU) | 1995-08-08 | — | — | US | disclosed |
| EP-0463123-A1 | 1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE REMOVAL OF TOXIC METAL IONS AND RADIOACTIVE ISOTOPES FROM THE LIVING ORGANISM | ORSZAGOS "FREDERIC JOLIOT-CURIE" SUGARBIOLOGIA ES SUGAREGESZSEGUGYI KUTATO INTEZET (HU) | 1992-01-02 | — | — | EP | disclosed |
| WO-1991010655-A1 | 1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE REMOVAL OF TOXIC METAL IONS AND RADIOACTIVE ISOTOPES FROM THE LIVING ORGANISM | ORSZÁGOS 'FREDERIC JOLIOT-CURIE' SUGÁRBIOLÓGIAI ÉS SUGÁREGÉSZSÉGÜGYI KUTATÓ INTÉZET (HU) | 1991-07-25 | — | — | WO | disclosed |
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3993468-A | INCREASING SUCROSE CONTENT | MONSANTO COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |