SCHEMBL16728048

SCHEMBL16728048

CC[C@H]1O[C@@H](n2cc(I)c3c(Cl)ncnc32)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 19/20 0.46
▸ SLC29A1 Q99808 1/20 0.45
▸ PRMT5 O14744 1/20 0.32
▸ METTL3 Q86U44 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14680070 1.00 ADK (0.46) ADKSLC29A1PRMT5METTL3
SCHEMBL19603990 0.91 ADK (0.53) ADKSLC29A1PRMT5METTL3
SCHEMBL10178145 0.91 ADK (0.47) ADKSLC29A1PRMT5METTL3
SCHEMBL19603993 0.91 ADK (0.47) ADKSLC29A1PRMT5METTL3
SCHEMBL14680026 0.88 ADK (0.34) ADKSLC29A1PRMT5METTL3
SCHEMBL15483516 0.88 ADK (0.34) ADKSLC29A1PRMT5METTL3
SCHEMBL14680069 0.87 ADK (0.35) ADKSLC29A1PRMT5METTL3
SCHEMBL16728050 0.87 ADK (0.35) ADKSLC29A1PRMT5METTL3
SCHEMBL16728040 0.85 ADK (0.34) ADKSLC29A1PRMT5METTL3
SCHEMBL14680075 0.85 ADK (0.34) ADKSLC29A1PRMT5METTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200319-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2015-12-01 — — US disclosed
US-20150140559-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2015-05-21 — — US disclosed
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