Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 12/20 | 0.77 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16698876 | 0.92 | MBOAT4 (0.76) | MBOAT4OPRK1HSP90AA1HSP90AB1 | |
| SCHEMBL19311928 | 0.92 | MBOAT4 (0.76) | MBOAT4OPRK1HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL16718846 | 0.91 | MBOAT4 (0.74) | MBOAT4OPRK1HSP90AA1HSP90AB1 | |
| SCHEMBL16728370 | 0.91 | MBOAT4 (0.74) | MBOAT4FAAHOPRK1HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL19971786 | 0.91 | MBOAT4 (0.74) | MBOAT4OPRK1HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL16699518 | 0.91 | MBOAT4 (0.74) | MBOAT4OPRK1HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL19971787 | 0.91 | MBOAT4 (0.74) | MBOAT4OPRK1HSP90AA1HSP90AB1 | |
| SCHEMBL19971834 | 0.89 | MBOAT4 (0.84) | MBOAT4OPRK1 | |
| SCHEMBL19971835 | 0.89 | MBOAT4 (0.84) | MBOAT4OPRK1 | |
| SCHEMBL19971808 | 0.88 | MBOAT4 (0.71) | MBOAT4OPRK1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073281-A1 | SUBSTITUTED PIPERIDYL-ETHYL-PYRIMIDINE AS GHRELIN O-ACYL TRANSFERASE INHIBITOR | ELI LILLY AND COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |