Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.78 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.78 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.78 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminohippuric Acid SCHEMBL196513 | 0.88 | KDM4E (1.00) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Aminohippuric Acid SCHEMBL31038605 | 0.87 | KDM4E (0.96) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL17077349 | 0.82 | KDM4E (0.86) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Aminohippuric Acid SCHEMBL29414543 | 0.81 | KDM4E (0.68) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL12774556 | 0.80 | KDM4E (0.66) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Aminohippuric Acid SCHEMBL10336340 | 0.79 | KDM4E (0.81) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Aminohippuric Acid SCHEMBL27678715 | 0.79 | KDM4E (0.81) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL11107537 | 0.79 | KDM4E (0.80) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL13100942 | 0.79 | KDM4E (0.64) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL12468396 | 0.77 | KDM4E (0.76) | KDM4EMAPTHIF1ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222404-B1 | PROTEASE DETECTION | MOLOGIC LTD (GB) | 2018-08-01 | — | — | EP | disclosed |
| US-9376706-B2 | Protease detection | MOLOGIC LIMITED (GB) | 2016-06-28 | — | — | US | disclosed |
| US-20150152471-A1 | PROTEASE DETECTION | MOLOGIC LIMITED (GB) | 2015-06-04 | — | — | US | disclosed |
| US-8993253-B2 | Protease detection | MOLOGIC LTD (GB) | 2015-03-31 | — | — | US | disclosed |
| US-20110086370-A1 | Protease Detection | MOLOGIC LTD (GB) | 2011-04-14 | — | — | US | disclosed |
| EP-2222404-A2 | PROTEASE DETECTION | Mologic Ltd (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009063208-A2 | PROTEASE DETECTION | MOLOGIC LTD (GB) | 2009-05-22 | — | — | WO | disclosed |