Aminohippuric Acid

Aminohippuric Acid

SCHEMBL196513

Nc1ccc(C(=O)NCC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
MAPT P10636 1/20 1.00
HIF1A Q16665 1/20 1.00
SLC22A6 Q4U2R8 1/20 1.00
SLC22A8 Q8TCC7 1/20 1.00
CA1 P00915 3/20 0.64
CA2 P00918 3/20 0.64
ATM Q13315 1/20 0.56
LMNA P02545 3/20 0.52
MEN1 O00255 1/20 0.52
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52
APEX1 P27695 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAPK1 P28482 2/20 0.51
SLC22A2 O15244 1/20 0.51
SLC22A1 O15245 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminohippuric Acid SCHEMBL31038605 0.98 KDM4E (0.96) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL17077349 0.93 KDM4E (0.86) KDM4EMAPTHIF1ASLC22A6SLC22A8
Aminohippuric Acid SCHEMBL10336340 0.90 KDM4E (0.81) KDM4EMAPTHIF1ASLC22A6SLC22A8
Aminohippuric Acid SCHEMBL27678715 0.90 KDM4E (0.81) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL11107537 0.89 KDM4E (0.80) KDM4EMAPTHIF1ASLC22A6SLC22A8
Aminohippuric Acid SCHEMBL1672845 0.88 KDM4E (0.78) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL12468396 0.87 KDM4E (0.76) KDM4EMAPTHIF1ASLC22A6SLC22A8
Aminohippuric Acid SCHEMBL8362626 0.86 KDM4E (0.73) KDM4EMAPTHIF1ASLC22A6SLC22A8
Aminohippuric Acid SCHEMBL8351356 0.84 MAPT (0.71) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL1913984 0.84 KDM4E (0.72) KDM4EMAPTHIF1ASLC22A6SLC22A8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2512 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
US-20250258159-A1 DEVICE, METHOD AND SYSTEM FOR MONITORING IMMUNE SYSTEM RESPONSE Olaris, Inc. 2025-08-14 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
WO-2025068212-A1 USE OF A MARKER SET FOR PROSTATE CARCINOMA DIAGNOSTICS NUMARES AG (DE) 2025-04-03 WO claimed
US-20240390364-A1 Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions REID CHRISTOPHER BRIAN (US) 2024-11-28 US claimed
CN-118994618-A Hyperbranched photosensitive resin with photoinitiation groups and LDI solder resist ink thereof 深圳市百利合新材料发展有限公司 2024-11-22 CN claimed
EP-3405966-B1 HIGH-VOLTAGE DEVICES UNIV CALIFORNIA (US) 2024-10-02 EP claimed
CN-118688315-A Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds 复旦大学 2024-09-24 CN claimed
US-20240304399-A1 HIGH-VOLTAGE DEVICES UNIV CALIFORNIA (US) 2024-09-12 US claimed
EP-0113242-B1 CEPHALOSPORIN DERIVATIVES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-11-08 EP claimed
EP-0078642-B1 RADIOPHARMACEUTICAL COMPOSITION BASED ON TECHNETIUM-99M AND REAGENT FOR MAKING IT AMERSHAM INTERNATIONAL plc (GB) 1986-12-10 EP claimed
EP-0113242-A2 Cephalosporin derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-07-11 EP claimed
US-4453007-A FORMING CATIONIC SALT AND ANIONIC SALT WITH SEPARATE PORTIONS OF COMPOUND, MIXING, AND COLLECTING PRECIPITATE USV PHARMACEUTICAL CORPORATION (US) 1984-06-05 US claimed
US-4451451-A Radiopharmaceutical composition based on technetium-99m and reagent for making it AMERSHAM INTERNATIONAL PLC (GB) 1984-05-29 US claimed
EP-0029284-B1 METHOD FOR THE ELECTROPHORETIC SEPARATION OF PROTEINS, A BUFFER SOLUTION AND BUFFER COMPOSITIONS THEREFOR GELMAN SCIENCES, INC. (US) 1984-02-15 EP claimed
EP-0078642-A2 Radiopharmaceutical composition based on technetium-99m and reagent for making it AMERSHAM INTERNATIONAL plc (GB) 1983-05-11 EP claimed
US-4292162-A A SOLUTION OF TRIS BUFFER, HIPPURIC ACID, AND A WATER-SOLUBLE HIPPURATE GELMAN SCIENCES, INC. (US) 1981-09-29 US claimed
US-4292154-A USING A UREA-, AN AMIDE-, OR AMINOCARBOAMIDE-CONTAINING CARBOXYLIC ACID AND THE CORRESPONDING ACID SALT GELMAN SCIENCES, INC. (US) 1981-09-29 US claimed
EP-0000066-A1 Determination of aromatic aminocarboxylic acids. Warren-Teed Laboratories, Inc. (US) 1978-12-20 EP claimed