Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 11/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 9/20 | 0.53 |
| ▸ | BTK | Q06187 | 6/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21131257 | 0.94 | CSNK1E (0.56) | CSNK1ECSNK1DBTKRIPK2 | |
| SCHEMBL16699603 | 0.86 | CSNK1E (0.70) | CSNK1ECSNK1DBTKRIPK2 | |
| SCHEMBL16709077 | 0.83 | CSNK1E (0.67) | CSNK1ECSNK1DBTKRIPK2 | |
| SCHEMBL16709075 | 0.83 | CSNK1E (0.74) | CSNK1ECSNK1D | |
| SCHEMBL20748973 | 0.81 | CSNK1E (0.58) | CSNK1ECSNK1DBTKRIPK2 | |
| SCHEMBL16709076 | 0.80 | CSNK1E (0.57) | CSNK1ECSNK1DBTKRIPK2 | |
| SCHEMBL16700548 | 0.80 | CSNK1E (0.63) | CSNK1ECSNK1DBTKRIPK2 | |
| SCHEMBL16700458 | 0.79 | CSNK1E (0.68) | CSNK1ECSNK1D | |
| SCHEMBL16711462 | 0.78 | CSNK1E (0.67) | CSNK1ECSNK1D | |
| SCHEMBL20748857 | 0.78 | CSNK1E (0.52) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |