Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 5/20 | 0.33 |
| ▸ | JAK1 | P23458 | 5/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709109 | 0.71 | MEN1 (0.35) | KMT2AMEN1MMP13P2RX7JAK2 | |
| SCHEMBL26855934 | 0.70 | KMT2A (0.47) | KMT2AMEN1MMP13P2RX7GPR119 | |
| SCHEMBL25284834 | 0.69 | KMT2A (0.47) | KMT2AMEN1MMP13P2RX7GPR119 | |
| SCHEMBL16709103 | 0.69 | MEN1 (0.35) | KMT2AMEN1MMP13P2RX7JAK2 | |
| SCHEMBL18991406 | 0.69 | KMT2A (0.46) | KMT2AMEN1MMP13P2RX7GPR119 | |
| SCHEMBL27229006 | 0.68 | KMT2A (0.44) | KMT2AMEN1MMP13P2RX7JAK2 | |
| SCHEMBL27228949 | 0.68 | KMT2A (0.45) | KMT2AMEN1MMP13P2RX7GPR119 | |
| SCHEMBL29045144 | 0.68 | KMT2A (0.45) | KMT2AMEN1MMP13P2RX7GPR119 | |
| SCHEMBL26907080 | 0.68 | KMT2A (0.45) | KMT2AMEN1MMP13P2RX7GPR119 | |
| SCHEMBL8827499 | 0.66 | GPR119 (0.45) | KMT2AMEN1MMP13P2RX7GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |