Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24181345 | 1.00 | GAA (0.83) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL12029057 | 0.91 | GAA (1.00) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL12028883 | 0.91 | GAA (1.00) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL3077457 | 0.91 | GAA (1.00) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL26273265 | 0.90 | GAA (0.83) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL6625137 | 0.89 | GAA (0.69) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL13452773 | 0.88 | GAA (0.79) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL15011529 | 0.86 | GAA (0.83) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL15010734 | 0.86 | GAA (0.83) | GAAALDH1A1TDP1RECQLCYP1A2 | |
| SCHEMBL22326350 | 0.85 | GAA (0.88) | GAAALDH1A1TDP1RECQLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141624-A1 | Anti-CD70 Antibody Drug Conjugates | AMBRX, INC. (US) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141624-A1 | Anti-CD70 Antibody Drug Conjugates | CD74, CD63, CD47 | GAA 438/4885ALDH1A1 868/4885TDP1 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.