Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 2/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672940 | 0.81 | BRD4 (0.35) | BRD4ESR1ESR2BRD2BRD3 | |
| SCHEMBL1672939 | 0.81 | BRD4 (0.35) | BRD4ESR1ESR2BRD2BRD3 | |
| SCHEMBL1670669 | 0.78 | BRD4 (0.32) | BRD4TAS2R8 | |
| SCHEMBL1670943 | 0.78 | BRD4 (0.35) | BRD4FTO | |
| SCHEMBL1670328 | 0.76 | BRD4 (0.33) | BRD4 | |
| SCHEMBL1671035 | 0.75 | BRD4 (0.33) | BRD4ERN1 | |
| SCHEMBL1670960 | 0.74 | — | — | |
| SCHEMBL1670276 | 0.74 | BRD4 (0.35) | BRD4NPC1TTRERN1 | |
| SCHEMBL12986085 | 0.74 | BRD4 (0.34) | BRD4 | |
| SCHEMBL12986674 | 0.74 | BRD4 (0.32) | BRD4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |