Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670665 | 0.80 | BRD4 (0.32) | BRD4 | |
| SCHEMBL1670663 | 0.80 | BRD4 (0.32) | BRD4 | |
| SCHEMBL1672942 | 0.78 | BRD4 (0.35) | BRD4TAS2R8 | |
| SCHEMBL1670328 | 0.77 | BRD4 (0.33) | BRD4EDNRA | |
| SCHEMBL1670700 | 0.76 | ERN1 (0.40) | BRD4EDNRATAS2R8 | |
| SCHEMBL12986085 | 0.74 | BRD4 (0.34) | BRD4MMP1MMP2MMP9MMP13 | |
| SCHEMBL12986674 | 0.74 | BRD4 (0.32) | BRD4MMP1MMP2MMP9MMP13 | |
| SCHEMBL1670574 | 0.74 | BRD4 (0.32) | BRD4TAS2R8 | |
| SCHEMBL1670571 | 0.74 | BRD4 (0.32) | BRD4TAS2R8 | |
| SCHEMBL1671035 | 0.73 | BRD4 (0.33) | BRD4EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |