⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1697297 | 0.65 | — | — | |
| SCHEMBL1671185 | 0.65 | — | — | |
| SCHEMBL5615165 | 0.65 | — | — | |
| SCHEMBL13431331 | 0.64 | — | — | |
| SCHEMBL458470 | 0.64 | — | — | |
| SCHEMBL1170651 | 0.62 | MAPT (0.35) | — | |
| SCHEMBL11803203 | 0.62 | MAPT (0.35) | — | |
| SCHEMBL1170650 | 0.62 | MAPT (0.35) | — | |
| SCHEMBL18007273 | 0.62 | — | — | |
| SCHEMBL19928385 | 0.62 | MAPT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955803-B | 3 aminopiperidines are prepared by nitro tetrahydropyridine precursor | 斯洛文尼亚莱柯制药股份有限公司 | 2017-11-28 | — | — | CN | disclosed |
| US-9796660-B2 | Gamma amino acid building blocks | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-10-24 | — | — | US | disclosed |
| US-20160280632-A1 | GAMMA AMINO ACID BUILDING BLOCKS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-09-29 | — | — | US | disclosed |
| US-9382291-B2 | Gamma amino acid building blocks | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150148523-A1 | GAMMA AMINO ACID BUILDING BLOCKS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-05-28 | — | — | US | disclosed |
| US-8664356-B2 | Gamma amino acid building blocks | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20110118440-A1 | GAMMA AMINO ACID BUILDING BLOCKS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-05-19 | — | — | US | disclosed |
| WO-2011047190-A1 | GAMMA AMINO ACID BUILDING BLOCKS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-04-21 | — | — | WO | disclosed |