SCHEMBL16730

SCHEMBL16730

OC1=NCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5425637 0.82
SCHEMBL3742115 0.67 NISCH (0.56)
SCHEMBL223938 0.63
SCHEMBL3536840 0.63
SCHEMBL4953373 0.63
SCHEMBL2288651 0.62
Ethylene Thiourea SCHEMBL19022294 0.62 ALDH1A1 (0.40)
SCHEMBL111668 0.62
Ethylene Thiourea SCHEMBL137081 0.62
SCHEMBL11563018 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119592087-A High-strength composite modified emulsified asphalt material and preparation method and application thereof 科之杰新材料集团有限公司 2025-03-11 CN claimed
CN-119463052-A Mud-resistant foam-stabilizing slump-retaining material and preparation method thereof 科之杰新材料集团(广东)有限公司 2025-02-18 CN claimed
CN-117551491-A Flame-retardant hydraulic oil and preparation method and application thereof 中国石油化工股份有限公司 2024-02-13 CN claimed
CN-113976529-A Cleaning method of copper target material 宁波江丰电子材料股份有限公司 2022-01-28 CN claimed
CN-110241425-A A kind of high-sulfur corrosion inhibiter for oil-gas gathering and transportation process 威海翔泽新材料科技有限公司 2019-09-17 CN claimed
EP-3143059-B1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2018-01-10 EP claimed
US-20170088659-A1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2017-03-30 US claimed
EP-3143059-A1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS Covestro Deutschland AG (DE) 2017-03-22 EP claimed
WO-2015173110-A1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2015-11-19 WO claimed
CN-104021854-A Sealing anti-explosion cable ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN claimed
CN-104021848-A Torsional tensile transmission control cable ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN claimed
CN-104021874-A Anti-torque type communication cable of flat structure ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN claimed
CN-104021866-A Heat dissipation type flat cable ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN claimed
CN-101805293-B 1 (dimethylamino) ethyl, 3-hydroxy-imidazoline hydrochloride and preparation method thereof SHIBAO NIE 2011-08-24 CN claimed
CN-101805293-A 1 (dimethylamino) ethyl, 3-hydroxy-imidazoline hydrochloride and preparation method thereof SHIBAO NIE 2010-08-18 CN claimed
EP-1426361-B1 Novel composition containing a bi-cyclic compound and a glyceride SUCAMPO AG (CH) 2008-07-30 EP claimed
CN-1045109-C Concentrated fabric softener compositions containing biodegradable fabric softeners PROCTER & GAMBLE (US) 1999-09-15 CN claimed
CN-1082101-A The concentrated fabric softener compositions that contains biodegradable fabric softener PROCTER & GAMBLE (US) 1994-02-16 CN claimed
EP-0341053-A1 Semi-polar hyperdispersants for pigment bases SUN CHEMICAL CORPORATION (US) 1989-11-08 EP claimed
EP-3690009-B1 FUEL ADDITIVE MIXTURE PROVIDING RAPID INJECTOR CLEAN-UP IN HIGH PRESSURE GASOLINE ENGINES AFTON CHEMICAL CORP (US) 2026-01-28 EP disclosed
CN-119592087-A High-strength composite modified emulsified asphalt material and preparation method and application thereof 科之杰新材料集团有限公司 2025-03-11 CN disclosed
CN-119463052-A Mud-resistant foam-stabilizing slump-retaining material and preparation method thereof 科之杰新材料集团(广东)有限公司 2025-02-18 CN disclosed
CN-114174612-B Inverted roof 匹兹堡康宁欧洲股份有限公司 2024-03-08 CN disclosed
CN-117551491-A Flame-retardant hydraulic oil and preparation method and application thereof 中国石油化工股份有限公司 2024-02-13 CN disclosed
CN-117226609-A Surface treatment method of copper block, heat sink block and electronic packaging material 佛山华智新材料有限公司 2023-12-15 CN disclosed
CN-111500329-B Fuel additive mixture providing rapid injector cleaning in high pressure gasoline engines 雅富顿化学公司 2023-10-20 CN disclosed
US-11390821-B2 Fuel additive mixture providing rapid injector clean-up in high pressure gasoline engines AFTON CHEMICAL CORPORATION (US) 2022-07-19 US disclosed
CN-114174612-A Inverted roof 匹兹堡康宁欧洲股份有限公司 2022-03-11 CN disclosed
CN-113976529-A Cleaning method of copper target material 宁波江丰电子材料股份有限公司 2022-01-28 CN disclosed
CN-108136358-B Process for preparing an aqueous dispersion of microparticles 巴斯夫欧洲公司 2021-09-10 CN disclosed
CN-111500329-A Fuel additive mixture providing rapid injector cleaning in high pressure gasoline engines 雅富顿化学公司 2020-08-07 CN disclosed
US-20200248089-A1 Fuel Additive Mixture Providing Rapid Injector Clean-up in High Pressure Gasoline Engines AFTON CHEMICAL CORPORATION 2020-08-06 US disclosed
EP-3690009-A1 FUEL ADDITIVE MIXTURE PROVIDING RAPID INJECTOR CLEAN-UP IN HIGH PRESSURE GASOLINE ENGINES Afton Chemical Corporation (US) 2020-08-05 EP disclosed
CN-111378974-A Polyethylene glycol-coupled oleic acid imidazoline water-soluble corrosion inhibitor and preparation method thereof 陕西日新石油化工有限公司 2020-07-07 CN disclosed
EP-2927218-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-07-04 EP disclosed
EP-3143059-B1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2018-01-10 EP disclosed
US-9725423-B2 Tetrazolinone compound and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-20170088659-A1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2017-03-30 US disclosed
EP-3143059-A1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS Covestro Deutschland AG (DE) 2017-03-22 EP disclosed
EP-2609253-B1 PAPERMAKING ADDITIVES FOR ROLL RELEASE IMPROVEMENT SOLENIS TECHNOLOGIES CAYMAN LP (CH) 2016-10-26 EP disclosed
WO-2015173110-A1 CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2015-11-19 WO disclosed
US-20150299146-A1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-22 US disclosed
EP-2927218-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-07 EP disclosed
US-8865263-B2 Papermaking additives for roll release improvement SOLENIS TECHNOLOGIES, L.P. (US) 2014-10-21 US disclosed
CN-104021848-A Torsional tensile transmission control cable ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN disclosed
CN-104021854-A Sealing anti-explosion cable ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN disclosed
CN-104021874-A Anti-torque type communication cable of flat structure ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN disclosed
CN-104021866-A Heat dissipation type flat cable ANHUI AICS SCIENCE & TECHNOLOGY GROUP CO LTD 2014-09-03 CN disclosed
EP-2121621-B1 LXR AND FXR MODULATORS EXELIXIS PATENT CO LLC (US) 2014-05-07 EP disclosed
CN-103360708-A Oil-resistant acrylic rubber sealing pad for transformer and preparation method thereof ANHUI CHUNHUI INSTR CABLE GROUP CO LTD 2013-10-23 CN disclosed
EP-2609253-A1 PAPERMAKING ADDITIVES FOR ROLL RELEASE IMPROVEMENT Hercules Incorporated (US) 2013-07-03 EP disclosed
CN-101948251-B Starching slurry of glass fiber yarn and production method by using same P D JVSHI INTERGLAS CO LTD 2012-07-25 CN disclosed
WO-2012027253-A1 PAPERMAKING ADDITIVES FOR ROLL RELEASE IMPROVEMENT HERCULES INCORPORATED (US) 2012-03-01 WO disclosed
US-20120045587-A1 Papermaking Additives for Roll Release Improvement THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2012-02-23 US disclosed
CN-101805293-B 1 (dimethylamino) ethyl, 3-hydroxy-imidazoline hydrochloride and preparation method thereof SHIBAO NIE 2011-08-24 CN disclosed
US-7998995-B2 LXR and FXR modulators EXELIXIS PATENT COMPANY LLC (US) 2011-08-16 US disclosed
CN-101948251-A Starching slurry of glass fiber yarn and production method by using same P D JVSHI INTERGLAS CO LTD 2011-01-19 CN disclosed
CN-101805293-A 1 (dimethylamino) ethyl, 3-hydroxy-imidazoline hydrochloride and preparation method thereof SHIBAO NIE 2010-08-18 CN disclosed
US-20100069367-A1 LXR and FXR Modulators EXELIXIS, INC. (US) 2010-03-18 US disclosed
EP-2121621-A1 LXR AND FXR MODULATORS Exelixis, Inc. (US) 2009-11-25 EP disclosed
EP-1426361-B1 Novel composition containing a bi-cyclic compound and a glyceride SUCAMPO AG (CH) 2008-07-30 EP disclosed
WO-2008073825-A1 LXR AND FXR MODULATORS EXELIXIS, INC. (US) 2008-06-19 WO disclosed
US-20080090834-A1 SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS PFIZER INC 2008-04-17 US disclosed
WO-2008004117-A1 SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS PFIZER PRODUCTS INC. (US) 2008-01-10 WO disclosed
CN-1169519-C Cleaning, conditioning and styling hair care compsns. 2004-10-06 CN disclosed
CN-1105175-C Fabric softener compositions with reduced environmental impact PROCTER & GAMBLE (US) 2003-04-09 CN disclosed
EP-1135443-A1 BISMUTH OXIDE CATALYST FOR CATHODIC ELECTROCOATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-26 EP disclosed
US-20010020345-A1 Gasoline additive for direct injection gasoline engine NIPPON MITSUBISHI OIL CORPORATION 2001-09-13 US disclosed
US-6287483-B1 MIXING WITH AMINOPYRROLIDINE COMPOUND UNIROYAL CHEMICAL COMPANY, INC. 2001-09-11 US disclosed
EP-1122295-A1 GASOLINE ADDITIVE FOR DIRECT-INJECTION GASOLINE ENGINE Nippon Mitsubishi Oil Corporation (JP) 2001-08-08 EP disclosed
EP-0658549-B1 Pyrimidine derivatives, process for their preparation and their use as herbicide LUCKY LTD (KR) 2001-05-23 EP disclosed
EP-1082280-A1 METHOD FOR STABILIZING UNSATURATED ORGANIC COMPOUNDS FROM POLYMERIZATION UNIROYAL CHEMICAL COMPANY, Inc. (US) 2001-03-14 EP disclosed
US-6156823-A Bismuth oxide catalyst for cathodic electrocoating compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-12-05 US disclosed
EP-1017679-A1 PROCESS FOR THE PREPARATION OF IMIDAZOLINE DERIVATIVES UNIROYAL CHEMICAL COMPANY, Inc. (US) 2000-07-12 EP disclosed
WO-2000034398-A1 BISMUTH OXIDE CATALYST FOR CATHODIC ELECTROCOATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-15 WO disclosed
WO-1999061396-A1 METHOD FOR STABILIZING UNSATURATED ORGANIC COMPOUNDS FROM POLYMERIZATION UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-12-02 WO disclosed
CN-1045109-C Concentrated fabric softener compositions containing biodegradable fabric softeners PROCTER & GAMBLE (US) 1999-09-15 CN disclosed
US-5928393-A ESTERIFIED, ALKOXYLATED TERTIARY AMINE COMPOUND; DETERGENT ANTISLUDGE/ANTIDEPOSIT AGENT FOR INTERNAL COMBUSTION ENGINES NIPPON OIL CO., LTD. (JP) 1999-07-27 US disclosed
CN-1222073-A Cleaning, conditioning and styling hair care compsns. STEPAN CO (US) 1999-07-07 CN disclosed
CN-1043885-C Novel herbicidal pyrimidine derivatives, process for preparation thereof and their use as herbicide LUCKY LTD (KR) 1999-06-30 CN disclosed
CN-1217017-A Fabric softener compositions with improved environmental impact PROCTER & GAMBLE (US) 1999-05-19 CN disclosed
WO-1999016754-A1 PROCESS FOR THE PREPARATION OF IMIDAZOLINE DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO disclosed
EP-0627483-B1 Additives formulated for motor-fuels containing at least one alkoxylated imidazo-oxazole compound INST FRANCAIS DU PETROLE (FR) 1998-12-23 EP disclosed
EP-0694089-B1 PROCESS FOR PRODUCING A HARDENED LEAD BATTERY ELECTRODE WARLIMONT HANS (DE) 1998-11-04 EP disclosed
CN-1195371-A Biodegradable fabric softener compositions with improved perfume longevity PROCTER & GAMBLE (US) 1998-10-07 CN disclosed
EP-0819753-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1998-01-21 EP disclosed
CN-1169157-A Fabric softener compositions with reduced environmental impact PROCTER & GAMBLE (US) 1997-12-31 CN disclosed
EP-0530094-B1 Motor fuel additive formulation comprising ester products and a detergent-dispersant agent INST FRANCAIS DU PETROLE (FR) 1997-05-21 EP disclosed
US-5521146-A Herbicidal pyrimidine derivatives, process for preparation thereof and their use as herbicide LUCKY LTD. (KR) 1996-05-28 US disclosed
EP-0694089-A1 PROCESS FOR PRODUCING A HARDENED LEAD BATTERY ELECTRODE Warlimont, Hans (DE) 1996-01-31 EP disclosed
US-5472457-A Mixed with detergent and fuel soluble, lubricating oils and/or polyethers; corrosion resistance, antideposit agents; internal combustion engines INSTITUT FRANCAIS DU PETROLE (FR) 1995-12-05 US disclosed
CN-1111623-A Novel herbicidal pyrimidine derivatives, process for preparation thereof and their use as herbicide LUCKY LTD (KR) 1995-11-15 CN disclosed
WO-1995022642-A1 PROCESS FOR PRODUCING A HARDENED LEAD BATTERY ELECTRODE WARLIMONT HANS (DE) 1995-08-24 WO disclosed
US-5433755-A Additive formulation for fuels incorporating ester function products and a detergent-dispersant INSTITUT FRANCAIS DU PETROLE (FR) 1995-07-18 US disclosed
EP-0658549-A1 Pyrimidine derivatives, process for their preparation and their use as herbicide LUCKY LTD. (KR) 1995-06-21 EP disclosed
US-5425788-A Internal combustion engines INSTITUT FRANCAIS DU PETROLE (FR) 1995-06-20 US disclosed
US-5424450-A Angiotensin II receptor blocking imidazolinone derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-13 US disclosed
EP-0627483-A1 Additives formulated for motor-fuels containing at least one alkoxylated imidazo-oxazole compound INSTITUT FRANCAIS DU PETROLE (FR) 1994-12-07 EP disclosed
EP-0482052-B1 COATING COMPOSITIONS COURTAULDS COATINGS HOLDINGS (GB) 1994-09-28 EP disclosed
EP-0599999-A1 ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-06-08 EP disclosed
EP-0596769-A1 Motor fuel additives compositions comprising nitrogenated products having two imide rings and motor fuels containing them INSTITUT FRANCAIS DU PETROLE (FR) 1994-05-11 EP disclosed
CN-1082101-A The concentrated fabric softener compositions that contains biodegradable fabric softener PROCTER & GAMBLE (US) 1994-02-16 CN disclosed
US-5278249-A Self-curable film forming copolymer COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1994-01-11 US disclosed
EP-0341053-B1 Semi-polar hyperdispersants for pigment bases SUN CHEMICAL CORP (US) 1993-12-15 EP disclosed
WO-1993004045-A1 ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-04 WO disclosed
EP-0530094-A1 Motor fuel additive formulation comprising ester products and a detergent-dispersant agent INSTITUT FRANCAIS DU PETROLE (FR) 1993-03-03 EP disclosed
EP-0349369-B1 COMPOSITION OBTAINED FROM HYDROXY-IMIDAZOLINES AND POLYAMINES, AND THEIR USE AS FUEL ADDITIVES Institut Français du Pétrole (FR) 1992-05-20 EP disclosed
EP-0482052-A1 COATING COMPOSITIONS. COURTAULDS COATINGS HOLDINGS (GB) 1992-04-29 EP disclosed
EP-0353116-B1 RECIPES OF NITROGENOUS ADDITIVES FOR ENGINE FUELS, AND ENGINE FUELS CONTAINING THEM Institut Français du Pétrole (FR) 1992-04-15 EP disclosed
US-5053056-A Reacted with an (poly)alkenyl-succinic acid or anhydride; detergent, antideposit anticorrosion agent INSTITUT FRANCAIS DU PETROLE (FR) 1991-10-01 US disclosed
WO-1991000894-A1 COATING COMPOSITIONS COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1991-01-24 WO disclosed
US-4976746-A Antideposit agents INSTITUT FRANCAIS DU PETROLE (FR) 1990-12-11 US disclosed
EP-0353116-A1 Recipes of nitrogenous additives for engine fuels, and engine fuels containing them Institut Français du Pétrole (FR) 1990-01-31 EP disclosed
EP-0349369-A1 Composition obtained from hydroxy-imidazolines and polyamines, and their use as fuel additives Institut Français du Pétrole (FR) 1990-01-03 EP disclosed
EP-0349369-A1 Composition obtained from hydroxy-imidazolines and polyamines, and their use as fuel additives Institut Français du Pétrole (FR) 1990-01-03 EP disclosed
EP-0341053-A1 Semi-polar hyperdispersants for pigment bases SUN CHEMICAL CORPORATION (US) 1989-11-08 EP disclosed
EP-0341053-A1 Semi-polar hyperdispersants for pigment bases SUN CHEMICAL CORPORATION (US) 1989-11-08 EP disclosed
EP-0069445-A1 Process for making benzimidazoles UNIROYAL, INC. (US) 1983-01-12 EP disclosed
US-4180084-A HAIR-CARE, ESPECIALLY SHAMPOO CIBA-GEIGY CORPORATION (US) 1979-12-25 US disclosed
US-4180084-A HAIR-CARE, ESPECIALLY SHAMPOO CIBA-GEIGY CORPORATION (US) 1979-12-25 US disclosed