Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705377 | 1.00 | CDA (0.64) | CDAMAPTLMNAMTORTHRB | |
| SCHEMBL24256534 | 1.00 | CDA (0.64) | CDAMAPTLMNAMTORTHRB | |
| SCHEMBL10445715 | 0.85 | CDA (0.54) | CDAMAPTLMNAMTORTHRB | |
| SCHEMBL23705296 | 0.78 | CDA (0.40) | CDAMAPTLMNAMTORTHRB | |
| SCHEMBL24256156 | 0.78 | CDA (0.40) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL11910465 | 0.78 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL21842491 | 0.78 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL2563757 | 0.78 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL21474114 | 0.78 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL1649826 | 0.78 | CDA (1.00) | CDAMAPTLMNAMTORTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015072784-A1 | MUTUAL PRODRUG COMPRISING SHORT CHAIN FATTY ACIDS AND ZEBULARINE OR 1'-CYANO-CYTARABINE FOR CANCER TREATMENT | KAINOS MEDICINE, INC. (KR) | 2015-05-21 | — | — | WO | disclosed |