Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 5/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.32 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.32 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709039 | 0.89 | RIPK2 (0.48) | RIPK2CSNK1ECSNK1DBTK | |
| SCHEMBL16709031 | 0.82 | CSNK1E (0.55) | RIPK2CSNK1ECSNK1DBTK | |
| SCHEMBL16728682 | 0.82 | CSNK1E (0.43) | CSNK1ECSNK1DBTKCACNB4CACNA1A | |
| SCHEMBL16728678 | 0.82 | CSNK1E (0.44) | CSNK1ECSNK1DBTKCACNB4CACNA1A | |
| SCHEMBL17718022 | 0.79 | RIPK2 (0.46) | RIPK2CSNK1ECSNK1DBTK | |
| SCHEMBL16709019 | 0.78 | CSNK1E (0.42) | CSNK1ECSNK1DBTK | |
| SCHEMBL16709041 | 0.78 | RIPK2 (0.50) | RIPK2CSNK1ECSNK1DBTK | |
| SCHEMBL16709045 | 0.77 | RIPK2 (0.44) | RIPK2CSNK1ECSNK1DBTKCTSS | |
| SCHEMBL16709035 | 0.77 | RIPK2 (0.48) | RIPK2CSNK1ECSNK1DBTK | |
| SCHEMBL16728683 | 0.77 | CSNK1E (0.40) | CSNK1ECSNK1DBTKKAT6AKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073763-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |