SCHEMBL1673065

SCHEMBL1673065

CC1CN(C(=O)OC(C)(C)C)CCN(C(=O)OC(C)(C)C)CCN(C(=O)OC(C)(C)C)CCN1CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 2/20 0.43
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NR1H2 P55055 1/20 0.41
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
EPHX2 P34913 1/20 0.40
SETD7 Q8WTS6 1/20 0.39
GPR119 Q8TDV5 6/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15347416 1.00 SLC6A9 (0.43) SLC6A9USP2SMN1; SMN2NR1H2HPGD
SCHEMBL23235715 0.99 SLC6A9 (0.44) SLC6A9USP2SMN1; SMN2NR1H2HPGD
SCHEMBL13812253 0.99 SLC6A9 (0.44) SLC6A9USP2SMN1; SMN2NR1H2HPGD
SCHEMBL3783647 0.90 NR1H2 (0.39) SLC6A9USP2SMN1; SMN2NR1H2HPGD
SCHEMBL3179712 0.86 NR1H2 (0.41) USP2SMN1; SMN2NR1H2HPGDMEN1
SCHEMBL3179703 0.86 NR1H2 (0.41) USP2SMN1; SMN2NR1H2HPGDMEN1
SCHEMBL3315088 0.84 NR1H2 (0.40) USP2SMN1; SMN2NR1H2MEN1ALDH1A1
SCHEMBL3319602 0.84 NR1H2 (0.40) USP2SMN1; SMN2NR1H2MEN1ALDH1A1
SCHEMBL17477191 0.84 NR1H2 (0.44) USP2SMN1; SMN2NR1H2HPGDMEN1
SCHEMBL17477192 0.84 NR1H2 (0.44) USP2SMN1; SMN2NR1H2HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940841-B9 COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM GUERBET SA (FR) 2017-04-19 EP disclosed
US-20170050988-A1 DOTAM DERIVATIVES FOR THERAPEUTIC USE SANOFI (FR) 2017-02-23 US disclosed
EP-1940841-B1 COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM GUERBET SA (FR) 2016-12-07 EP disclosed
US-8926945-B2 Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium GUERBET (FR) 2015-01-06 US disclosed
US-20110092806-A1 Compounds Comprising a Biological Target Recognizing Part, Coupled to a Signal Part Capable of Complexing Gallium GUEREBET (FR) 2011-04-21 US disclosed
US-20070014721-A1 Hydrazide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110092806-A1 Compounds Comprising a Biological Target Recognizing Part, Coupled to a Signal Part Capable of Complexing Gallium KLK3, IGF1R, GIPR SLC6A9 4319/4885USP2 3392/4885SMN1; SMN2 4882/4885
US-20070014721-A1 Hydrazide conjugates as imaging agents CA14, CA13, CA1 SLC6A9 2876/4885USP2 774/4885SMN1; SMN2 4296/4885
US-20170050988-A1 DOTAM DERIVATIVES FOR THERAPEUTIC USE SSTR2, SSTR5, SSTR3 SLC6A9 358/4885USP2 4447/4885SMN1; SMN2 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.