Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709013 | 0.90 | CNR2 (0.38) | KMOCNR2KMT2AKDM4EPOLB | |
| SCHEMBL16700430 | 0.85 | SMN1; SMN2 (0.47) | MEN1KMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL16730914 | 0.82 | NOTUM (0.38) | KMOKDM4EGAAFYNNOTUM | |
| SCHEMBL16699875 | 0.74 | KMO (0.41) | KMOMEN1KMT2AKDM4EPOLB | |
| SCHEMBL10958055 | 0.73 | KMO (0.50) | KMOMEN1KMT2AKDM4EPOLB | |
| SCHEMBL16699496 | 0.71 | KMO (0.45) | KMOCNR2MEN1KMT2AKDM4E | |
| SCHEMBL16709089 | 0.67 | DPP4 (0.38) | KMT2AKDM4EPOLBGAATSHR | |
| SCHEMBL32691592 | 0.66 | POLB (0.49) | KMOKDM4EPOLBGAA | |
| SCHEMBL17593064 | 0.66 | PHGDH (0.50) | KMT2AKDM4EPOLBRECQLGAA | |
| SCHEMBL27409568 | 0.65 | MAPT (0.52) | KMOMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073763-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |