Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 18/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.63 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.63 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.63 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.63 |
| ▸ | PRKDC | P78527 | 2/20 | 0.63 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.63 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.63 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.63 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.63 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.63 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ATR | Q13535 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18068256 | 0.94 | MTOR (0.67) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL16719264 | 0.91 | MTOR (0.61) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL18069550 | 0.89 | MTOR (0.60) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL16731009 | 0.88 | MTOR (0.58) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL18068255 | 0.87 | MTOR (0.81) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL16719263 | 0.86 | MTOR (0.70) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL23158114 | 0.85 | MTOR (0.78) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL6878221 | 0.85 | MTOR (0.69) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL16719179 | 0.84 | MTOR (0.68) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL11885747 | 0.83 | MTOR (0.74) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073804-A2 | METHOD OF BLOCKING TRANSMISSION OF MALARIAL PARASITE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-05-21 | — | — | WO | disclosed |