⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16766999 | 0.84 | LMNA (0.36) | — | |
| SCHEMBL2458453 | 0.84 | CCR1 (0.41) | — | |
| SCHEMBL17476685 | 0.82 | TP53 (0.33) | — | |
| SCHEMBL28408851 | 0.82 | KDM4E (0.33) | — | |
| SCHEMBL28313237 | 0.82 | — | — | |
| SCHEMBL7453710 | 0.80 | — | — | |
| SCHEMBL252441 | 0.78 | KDM4E (0.61) | — | |
| SCHEMBL5256319 | 0.78 | — | — | |
| SCHEMBL29429423 | 0.78 | KDM4E (0.61) | — | |
| SCHEMBL3984118 | 0.78 | CYP1A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820229-A | Method for preparing 3,3' -bipyrazole for large-scale synthesis | 西北大学 | 2024-04-05 | — | — | CN | claimed |
| CN-112341456-B | Substituted pyrazolyl pyrazole bisamide compound or salt, composition and application thereof acceptable as pesticide | 海利尔药业集团股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-111936667-B | Method for producing laminate | 大金工业株式会社 | 2022-12-13 | — | — | CN | claimed |
| WO-2021023292-A1 | SUBSTITUTED PYRAZOLYL PYRAZOLE BISAMIDE COMPOUND OR PESTICIDE ACCEPTABLE SALT OR COMPOSITION THEREOF, AND USE THEREOF | 海利尔药业集团股份有限公司 | 2021-02-11 | — | — | WO | claimed |
| CN-112341456-A | Substituted pyrazolyl pyrazole bisamide compound or salt and composition thereof acceptable as pesticide and application thereof | 海利尔药业集团股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| EP-2694509-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF TROPOMYOSIN-RELATED KINASES | PFIZER LTD (GB) | 2016-05-18 | — | — | EP | claimed |
| US-20140364415-A1 | PYRROLO[2,3-d]PYRIMIDINE TROPOMYSIN-RELATED KINASE INHIBITORS | PFIZER LIMITED (GB) | 2014-12-11 | — | — | US | claimed |
| US-8846698-B2 | Pyrrolo[2,3-d]pyrimidine tropomysin-related kinase inhibitors | PFIZER LIMITED (US) | 2014-09-30 | — | — | US | claimed |
| EP-2694509-A1 | PYRROLO [2, 3 -D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF TROPOMYOSIN- RELATED KINASES | Pfizer Limited (GB) | 2014-02-12 | — | — | EP | claimed |
| US-20120258950-A1 | PYRROLO[2,3-d]PYRIMIDINE TROPOMYSIN-RELATED KINASE INHIBITORS | PFIZER LIMITED (GB) | 2012-10-11 | — | — | US | claimed |
| CN-1195339-A | 4-thiocarbamoyl-1- (3-pyrazolyl) -pyrazoles and their use as herbicides | BAYER AG (DE) | 1998-10-07 | — | — | CN | claimed |
| WO-1998006702-A1 | SUBSTITUTED 1-(3-PYRAZOLYL)-PYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | claimed |
| WO-1998003506-A1 | SUBSTITUTED PYRAZOLYL-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH A HERBICIDAL EFFECT | HOECHST SCHERING AGREVO GMBH (DE) | 1998-01-29 | — | — | WO | claimed |
| WO-1997046536-A1 | SUBSTITUTED PYRAZOLYL-PYRAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-12-11 | — | — | WO | claimed |
| EP-0643700-B1 | NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-09-11 | — | — | EP | claimed |
| US-5405829-A | Substituted pyrazolypyrazoles and their use as herbicides | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | claimed |
| EP-0643700-A1 | NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES. | SCHERING AG (DE) | 1995-03-22 | — | — | EP | claimed |
| CN-1073440-A | The pyrazolyl-pyrazole of new replacement, its preparation method, and their intermediate and they are as the purposes of weedicide | SCHERING AG (DE) | 1993-06-23 | — | — | CN | claimed |
| WO-1993010100-A1 | NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | claimed |
| EP-0542388-A1 | New substituted pyrazolylpyrazoles, processes for their preparation, as well as intermediates, and their use as herbicides | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | claimed |