Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP5C | P53041 | 2/20 | 0.47 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.47 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 1/20 | 0.47 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18047220 | 1.00 | PPP5C (0.47) | PPP5CPPP2CATFPI2NPY4RPPM1B | |
| SCHEMBL16731419 | 1.00 | PPP5C (0.47) | PPP5CPPP2CATFPI2NPY4RPPM1B | |
| SCHEMBL16731276 | 0.91 | TFPI2 (0.56) | PPP5CPPP2CATFPI2NPY4RPPM1B | |
| SCHEMBL16731299 | 0.91 | TFPI2 (0.56) | PPP5CPPP2CATFPI2NPY4RPPM1B | |
| SCHEMBL17585970 | 0.91 | TFPI2 (0.56) | PPP5CPPP2CATFPI2NPY4RPPM1B | |
| SCHEMBL16731414 | 0.87 | MGLL (0.37) | MGLLFAAHALDH1A1MAPTTHRB | |
| SCHEMBL16731300 | 0.82 | TFPI2 (0.62) | PPP5CPPP2CATFPI2NPY4RPPM1B | |
| SCHEMBL16731415 | 0.79 | PPARG (0.39) | PPP5CPPP2CATFPI2NPY4RALDH1A1 | |
| SCHEMBL16731269 | 0.79 | PPARG (0.39) | PPP5CPPP2CATFPI2NPY4RALDH1A1 | |
| SCHEMBL18073234 | 0.77 | TFPI2 (0.50) | PPP5CPPP2CATFPI2NPY4RPPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073802-A1 | PROTEIN PHOSPHATASE INHIBITORS THAT CROSS THE BLOOD BRAIN BARRIER | LIXTE BIOTECHNOLOGY, INC. (US) | 2015-05-21 | — | — | WO | disclosed |