Metyridine

Metyridine

SCHEMBL167318

COCCc1ccccn1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.55
HRH3 Q9Y5N1 1/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
ALDH1A1 P00352 3/20 0.53
LMNA P02545 2/20 0.53
TAAR1 Q96RJ0 1/20 0.53
ALOX15 P16050 1/20 0.53
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CYP1A2 P05177 3/20 0.47
CYP2C19 P33261 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metyridine SCHEMBL30481621 1.00 HRH1 (0.55) HRH1HRH3CA12CA1CA2
SCHEMBL29436004 0.89 CA12 (0.49) HRH1HRH3CA12CA1CA2
SCHEMBL6859512 0.88 HRH1 (0.55) HRH1HRH3CA12CA1CA2
Metyridine SCHEMBL8450058 0.87 CA12 (0.44) HRH1HRH3CA12CA1CA2
SCHEMBL8243986 0.86 HRH1 (0.58) HRH1HRH3CA12CA1CA2
SCHEMBL7449287 0.83 HRH1 (0.59) HRH1HRH3CA12CA1CA2
SCHEMBL13451317 0.82 CYP1A2 (0.59) HRH1HRH3ALDH1A1LMNATAAR1
SCHEMBL13451318 0.81 KDM4E (0.56) HRH3ALDH1A1CYP1A2CYP2C19TDP1
SCHEMBL27952913 0.81 CA12 (0.45) HRH1HRH3CA12CA1CA2
SCHEMBL18704138 0.81 HRH1 (0.51) HRH1HRH3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025229128-A1 ANTI-INFLAMMATORY POLYPEPTIDES DERIVED FROM HELMINTHIC GLUTAMATE DEHYDROGENASE (HEGDH), METHODS AND USES THEREOF Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2025-11-06 WO claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN claimed
CN-118434765-A BCMA monoclonal antibodies and antibody-drug conjugates 杭州多禧生物科技有限公司 2024-08-02 CN claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-117384085-A Method for preparing 2-vinyl pyridine by catalytic pyrolysis 江苏亚泰化工有限公司 2024-01-12 CN claimed
CN-116854626-A Preparation method of 2-vinyl pyridine 河南省科学院高新技术研究中心 2023-10-10 CN claimed
CN-116143678-A Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof 杭州多禧生物科技有限公司 2023-05-23 CN claimed
US-20170135347-A1 INSECTICIDAL, MITICIDAL, NEMATICIDAL, MOLLUSCICIDAL, MICROBICIDAL, OR BACTERICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-05-18 US claimed
CN-106659160-A Insecticide, miticide, nematicide, molluscicide, disinfectant, or bactericide composition, and pest control method 日产化学工业株式会社 2017-05-10 CN claimed
US-7247645-B2 Dihydropyridine derivatives AJINOMOTO CO., INC. (JP) 2007-07-24 US claimed
US-20040249099-A1 Acrylic esters of 2-cyano-2, 4 pentenedioic acid CHEMENCE, INC. 2004-12-09 US claimed
US-20020147222-A1 Dihydropyridine derivatives AJINOMOTO CO. INC (JP) 2002-10-10 US claimed
EP-1191021-A1 DIHYDROPYRIDINE DERIVATIVE Ajinomoto Co., Inc. (JP) 2002-03-27 EP claimed
US-20020025477-A1 Non-aqueous electrolytic solution and secondary battery containing same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-02-28 US claimed
EP-1172878-A2 Non-aqueous electrolytic solution and secondary battery containing same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-01-16 EP claimed
WO-1992009651-A1 POLYCYANOACRYLATE FOAM CHEMENCE LIMITED (GB) 1992-06-11 WO claimed
WO-1990009096-A2 METHOD OF SCREENING AND CLASSIFYING COMPOUNDS CAMBRIDGE NEUROSCIENCE RESEARCH, INC. (US) 1990-08-23 WO claimed
EP-0021758-B1 VETERINARY PREPARATIONS FOR RUMINANT ANIMALS BEECHAM GROUP PLC (GB) 1984-04-04 EP claimed
US-4009266-A METHOD OF TREATMENT OF NEMATODE PARASITE INFECTIONS IN DOMESTIC ANIMALS AYALEW LIYEW 1977-02-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170135347-A1 INSECTICIDAL, MITICIDAL, NEMATICIDAL, MOLLUSCICIDAL, MICROBICIDAL, OR BACTERICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST DDT, ACHE, DRD5 HRH1 1368/4885HRH3 1903/4885CA12 4139/4885
US-20020147222-A1 Dihydropyridine derivatives CACNA1B, CACNA1D, CACNA1C HRH1 596/4885HRH3 1086/4885CA12 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.