Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16733096 | 1.00 | IDO1 (0.41) | IDO1GAATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL10437819 | 0.82 | IDO1 (0.41) | IDO1GAATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL16943489 | 0.82 | TP53 (0.39) | IDO1GAATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL17803033 | 0.79 | TP53 (0.44) | IDO1GAATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL21702260 | 0.79 | TP53 (0.44) | IDO1GAATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9550358 | 0.79 | TP53 (0.44) | IDO1GAATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL17803098 | 0.77 | TP53 (0.43) | IDO1GAATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL13896036 | 0.77 | PLG (0.42) | IDO1TP53 | |
| SCHEMBL9948592 | 0.77 | TP53 (0.43) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL2948892 | 0.76 | TP53 (0.56) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758480-B2 | 1-(cycloalkyl-carbonyl)proline derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9718840-B2 | Condensed 5-oxazolidinone derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20170022218-A1 | CONDENSED 5-OXAZOLIDINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-01-26 | — | — | US | disclosed |
| EP-3095786-A1 | CONDENSED 5-OXAZOLIDINONE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-20150210640-A1 | 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2015-07-30 | — | — | US | disclosed |
| EP-2876105-A1 | 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2015-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210640-A1 | 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE | RB1, F2, SFPQ | IDO1 1797/4885GAA 3950/4885TP53 396/4885 |
| US-20170022218-A1 | CONDENSED 5-OXAZOLIDINONE DERIVATIVE | F2, SERPINC1, F12 | IDO1 2804/4885GAA 4585/4885TP53 3074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.