Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL29229320 | 0.82 | LMNA (0.40) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL27604496 | 0.82 | CYP2C9 (0.50) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL12761 | 0.82 | CYP2C9 (0.46) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL1527414 | 0.82 | CYP2C9 (0.46) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL29707714 | 0.82 | CYP2C9 (0.46) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL9016497 | 0.82 | CYP2C9 (0.46) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL1154916 | 0.78 | CYP2C9 (0.47) | CYP2C9GRIN2DGRIN3BGRIN1GRIN2A | |
| Adamantane SCHEMBL27840036 | 0.78 | LMNA (0.44) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL1206076 | 0.78 | GRIN2D (0.38) | CYP2C9LMNANFKB1GRIN2DGRIN3B | |
| Adamantane SCHEMBL25171693 | 0.77 | TSHR (0.50) | CYP2C9LMNANFKB1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432025-B | Adamantane sulfonamide compound and preparation and application thereof | 重庆医科大学 | 2023-06-09 | — | — | CN | claimed |
| CN-116640081-A | Adamantane sulfonamide compound as well as preparation method and application thereof | 重庆医科大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-106432025-B | Adamantane sulfonamide compound and preparation and application thereof | 重庆医科大学 | 2023-06-09 | — | — | CN | disclosed |
| EP-2875816-A1 | N-(3-hydroxy-5,7-dimethyladamantan-1-yl)-2-(3-oxobenzo[d]isothiazol-2(3h)-yl)acetamide as a novel inhibitor for staphylococcus aureus sortase a | Latvian Biomedical Research and Study Centre (LV) | 2015-05-27 | — | — | EP | disclosed |