Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 14/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735481 | 0.80 | CCR2 (0.51) | CCR2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL16735455 | 0.79 | CCR2 (0.50) | CCR2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL9940180 | 0.78 | CCR2 (0.51) | CCR2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL16735513 | 0.76 | CCR2 (0.48) | CCR2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL19406113 | 0.74 | CCR2 (0.73) | CCR2MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL16735458 | 0.74 | CCR2 (0.51) | CCR2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL16735464 | 0.74 | CCR2 (0.48) | CCR2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL16735460 | 0.74 | CCR2 (0.50) | CCR2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL9936703 | 0.71 | CCR2 (0.67) | CCR2MAPTHTTMEN1KMT2A | |
| SCHEMBL9968092 | 0.71 | CCR2 (0.77) | CCR2MEN1KMT2ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955173-B1 | 1,2-BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2017-10-04 | — | — | EP | claimed |
| EP-2651901-B1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2015-05-27 | — | — | EP | claimed |