Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008796 | 0.86 | TLR7 (0.48) | TLR7GRM2 | |
| SCHEMBL1059384 | 0.86 | TLR7 (0.48) | TLR7GRM2 | |
| SCHEMBL1009183 | 0.85 | TLR7 (0.46) | TLR7GRM2 | |
| SCHEMBL1009149 | 0.84 | TLR7 (0.53) | TLR7GRM2 | |
| SCHEMBL15345852 | 0.84 | TLR7 (0.65) | TLR7GRM2 | |
| SCHEMBL1527462 | 0.84 | TLR7 (0.65) | TLR7GRM2 | |
| SCHEMBL1527588 | 0.84 | TLR7 (0.65) | TLR7GRM2 | |
| SCHEMBL1703699 | 0.83 | TLR7 (0.48) | TLR7GRM2 | |
| SCHEMBL1527519 | 0.82 | TLR7 (0.64) | TLR7GRM2 | |
| SCHEMBL11891212 | 0.82 | TLR7 (0.64) | TLR7GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-B1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2015-05-27 | — | — | EP | disclosed |