Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL17113605 | 1.00 | SLC7A5 (0.41) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL1673654 | 1.00 | SLC7A5 (0.41) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL28064125 | 1.00 | SLC7A5 (0.41) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL8819187 | 0.95 | SLC7A5 (0.38) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL27483533 | 0.95 | SLC7A5 (0.38) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL8819193 | 0.95 | SLC7A5 (0.38) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL7581387 | 0.93 | PTGS1 (0.41) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL4678808 | 0.93 | PTGS1 (0.41) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL17628714 | 0.92 | BLM (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL6534153 | 0.92 | BLM (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227820-B1 | OLIGOSACCHARIDE ALDONIC ACIDS AND THEIR TOPICAL USE | YU RUEY J (US) | 2006-04-19 | — | — | EP | claimed |
| US-20200208132-A1 | RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF | PROTEON THERAPEUTICS, INC. (US) | 2020-07-02 | — | — | US | disclosed |
| US-10308924-B2 | Nucleic acid molecules encoding autoactivating type I pancreatic proelastase proteins | PROTEON THERAPEUTICS, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-10301612-B2 | Recombinant elastase proteins and methods of manufacturing and use thereof | PROTEON THERAPEUTICS, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180208918-A1 | NUCLEIC ACID MOLECULES ENCODING AUTOACTIVATING TYPE I PANCREATIC PROELASTASE PROTEINS | PROTEON THERAPEUTICS, INC. (US) | 2018-07-26 | — | — | US | disclosed |
| US-20180155703-A1 | RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF | PROTEON THERAPEUTICS, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| US-20160319267-A1 | RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF | PROTEON THERAPEUTICS, INC. (US) | 2016-11-03 | — | — | US | disclosed |
| US-20150322420-A9 | RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF | PROTEON THERAPEUTICS, INC. | 2015-11-12 | — | — | US | disclosed |
| US-20150166974-A1 | Recombinant Elastase Proteins and Methods of Manufacturing and Use Thereof | PROTEON THERAPEUTICS, INC. (US) | 2015-06-18 | — | — | US | disclosed |
| CN-103702982-A | Micronized crystals of atorvastatin hemicalcium | NETHERLANDS BV OF DSM SINOCHEM PHARMACEUTICALS PTE LTD | 2014-04-02 | — | — | CN | disclosed |
| WO-2002083176-A2 | BIOMATERIALS COMPRISING A MELANOCYTE STIMULATING HORMONE (MSH), AND METHOD OF FORMING | UNIVERSITY OF SHEFFIELD (GB) | 2002-10-24 | — | — | WO | disclosed |
| CN-1371421-A | Tankyrase 2 materials and methods | ICOS CORP (US) | 2002-09-25 | — | — | CN | disclosed |
| CN-1370238-A | Materials and methods for human poly (ADP-nucleic acid) polymerase 2 | ICOS CORP (US) | 2002-09-18 | — | — | CN | disclosed |
| CN-1340103-A | Complex-forming proteins | AVENTIS PHARMA GMBH (DE) | 2002-03-13 | — | — | CN | disclosed |
| WO-2000075316-A1 | METHODS AND COMPOSITIONS FOR INHIBITING NEOPLASTIC CELL GROWTH | GENENTECH, INC. (US) | 2000-12-14 | — | — | WO | disclosed |
| US-6020312-A | Synthetic antibiotics | NCE PHARMACEUTICALS, INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0783316-A4 | SYNTHETIC ANTIBIOTICS | CERES TECHNOLOGIES INC (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5766916-A | FUSION PROTEINS; VIRICIDES | GENELABS TECHNOLOGIES, INC. (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0783316-A1 | SYNTHETIC ANTIBIOTICS | CERES TECHNOLOGIES, INC. (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996008264-A1 | SYNTHETIC ANTIBIOTICS | CERES TECHNOLOGIES, INC. (US) | 1996-03-21 | — | — | WO | disclosed |