Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191427 | 0.82 | EGFR (0.38) | HMGCREGFRMAPTHTTPOLB | |
| SCHEMBL10984606 | 0.77 | HMGCR (0.40) | HMGCREGFRNR1I2MAPTHTT | |
| SCHEMBL39364 | 0.76 | HMGCR (0.62) | HMGCRNR1I2MAPTHTTPOLB | |
| SCHEMBL5428580 | 0.75 | HMGCR (0.61) | HMGCRNR1I2MAPTHTTPOLB | |
| SCHEMBL562987 | 0.75 | HMGCR (0.61) | HMGCRNR1I2MAPTHTTPOLB | |
| SCHEMBL10990560 | 0.75 | DHFR (0.37) | HMGCREGFRMEN1KMT2AGABRA1 | |
| SCHEMBL564169 | 0.75 | HMGCR (0.61) | HMGCRNR1I2MAPTHTTPOLB | |
| SCHEMBL28615117 | 0.75 | HMGCR (0.61) | HMGCRNR1I2MAPTHTTPOLB | |
| SCHEMBL13913134 | 0.74 | TSHR (0.50) | EGFRMAPTHTTPOLBPPARD | |
| SCHEMBL3803725 | 0.74 | HMGCR (0.49) | HMGCREGFRNR1I2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9117985-B2 | Silicone resin composition and an optical semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20150144987-A1 | SILICONE RESIN COMPOSITION AND AN OPTICAL SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-05-28 | — | — | US | disclosed |