Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.58 |
| ▸ | AKR1C4 | P17516 | 4/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 2/20 | 0.53 |
| ▸ | MAX | P61244 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16737198 | 0.86 | CTSV (0.54) | CTSVCTSLMYCMAXMPO | |
| SCHEMBL16737131 | 0.86 | CTSV (0.54) | AKR1C3AKR1C2CTSVCTSLMYC | |
| SCHEMBL16737106 | 0.86 | CTSV (0.54) | AKR1C3AKR1C2CTSVCTSLMYC | |
| SCHEMBL16737118 | 0.84 | MEN1 (0.57) | AKR1C3AKR1C2AKR1C4AKR1C1CTSV | |
| SCHEMBL16737204 | 0.83 | CDC25B (0.67) | AKR1C3AKR1C2AKR1C4AKR1C1CTSV | |
| SCHEMBL16737110 | 0.83 | AKR1C3 (0.71) | AKR1C3AKR1C2AKR1C4AKR1C1AR | |
| SCHEMBL22720115 | 0.83 | MYC (0.65) | AKR1C3AKR1C2AKR1C4AKR1C1CTSV | |
| SCHEMBL16737175 | 0.82 | MEN1 (0.53) | AKR1C3AKR1C2AKR1C4AKR1C1CTSV | |
| SCHEMBL9551960 | 0.80 | CTSV (0.78) | AKR1C3AKR1C2CTSVCTSLMYC | |
| SCHEMBL4164387 | 0.80 | CTSV (0.78) | AKR1C3AKR1C2CTSVCTSLMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834537-B2 | Compounds as chloride channel blocking agent | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-12-05 | — | — | US | claimed |
| US-20150148550-A1 | NOVEL COMPOUNDS AS CHLORIDE CHANNEL BLOCKING AGENT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-05-28 | — | — | US | claimed |
| US-9834537-B2 | Compounds as chloride channel blocking agent | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-12-05 | — | — | US | disclosed |
| US-20150148550-A1 | NOVEL COMPOUNDS AS CHLORIDE CHANNEL BLOCKING AGENT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148550-A1 | NOVEL COMPOUNDS AS CHLORIDE CHANNEL BLOCKING AGENT | CACNB2, CACNB1, CACNB4 | AKR1C3 3944/4885AKR1C2 3604/4885AKR1C4 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.