⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroacetone SCHEMBL10892409 | 0.90 | LMNA (0.44) | — | |
| Chloromethane SCHEMBL27614709 | 0.89 | — | — | |
| Methylamine SCHEMBL7860233 | 0.89 | — | — | |
| Methyl Alcohol SCHEMBL9120455 | 0.89 | — | — | |
| SCHEMBL22090 | 0.89 | — | — | |
| Ethyl Chloride SCHEMBL29281349 | 0.86 | — | — | |
| Acetamide SCHEMBL12076247 | 0.85 | LMNA (0.67) | — | |
| Acetamide SCHEMBL27839696 | 0.85 | — | — | |
| Urea SCHEMBL2725491 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL3108506 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |
| EP-3484875-B1 | PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS | LILLY CO ELI (US) | 2021-04-07 | — | — | EP | disclosed |
| EP-3298001-B1 | DGAT2 INHIBITORS | LILLY CO ELI (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10344018-B2 | Pyrazolylaminobenzimidazole derivatives as JAK inhibitors | ELI LILLY AND COMPANY (US) | 2019-07-09 | — | — | US | disclosed |
| US-10323019-B2 | Pyrazolylaminobenzimidazole derivatives as JAK inhibitors | ELI LILLY AND COMPANY (US) | 2019-06-18 | — | — | US | disclosed |
| US-20190177300-A1 | PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS | LILLY CO ELI (US) | 2019-06-13 | — | — | US | disclosed |
| EP-3484875-A1 | PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS | Eli Lilly and Company (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20180325873-A1 | PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS | ELI LILLY AND COMPANY | 2018-11-15 | — | — | US | disclosed |
| US-10053429-B2 | DGAT2 inhibitors | ELI LILLY AND COMPANY (US) | 2018-08-21 | — | — | US | disclosed |
| EP-3074381-B1 | NOVEL DGAT2 INHIBITORS | LILLY CO ELI (US) | 2018-07-04 | — | — | EP | disclosed |
| US-20180162825-A1 | NOVEL DGAT2 INHIBITORS | ELI LILY AND COMPANY (US) | 2018-06-14 | — | — | US | disclosed |
| CN-107635975-A | NOVEL DGAT2 INHIBITORS | 伊莱利利公司 | 2018-01-26 | — | — | CN | disclosed |
| WO-2018013486-A1 | PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS | ELI LILLY AND COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |
| EP-3074381-A1 | NOVEL DGAT2 INHIBITORS | Eli Lilly and Company (US) | 2016-10-05 | — | — | EP | disclosed |
| US-9073901-B2 | DGAT2 inhibitors | ELI LILLY AND COMPANY (US) | 2015-07-07 | — | — | US | disclosed |
| US-20150148358-A1 | NOVEL DGAT2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2015-05-28 | — | — | US | disclosed |
| WO-2015077299-A1 | NOVEL DGAT2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2015-05-28 | — | — | WO | disclosed |
| CN-101528033-A | Cropping systems for managing weeds | MONSANTO TECHNOLOGY LLC (US) | 2009-09-09 | — | — | CN | disclosed |