Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050963 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL31287272 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL8002198 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL12530114 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL1537645 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL380051 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL2617514 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL2617503 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL12772356 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT | |
| SCHEMBL312680 | 0.90 | MEN1 (0.38) | MEN1MAPK1KMT2ABTKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012048235-A1 | VITAMIN E FORMULATIONS OF SULFAMIDE NS3 INHIBITORS | NOVARTIS AG (CH) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012045280-A1 | SALTS AND POLYMORPHS OF SULFAMIDE NS3 INHIBITORS | NOVARTIS AG (CH) | 2012-04-12 | — | — | WO | disclosed |
| WO-2010116248-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2010-10-14 | — | — | WO | disclosed |
| WO-2007121125-A2 | HCV INHIBITORS | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |